Mezick Elizabeth J, Matthews Karen A, Hall Martica H, Richard Jennings J, Kamarck Thomas W
Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Psychophysiology. 2014 Jan;51(1):88-96. doi: 10.1111/psyp.12144. Epub 2013 Sep 9.
Short sleep has been related to incident cardiovascular disease, but physiological mechanisms accounting for this relationship are largely unknown. This study examines sleep duration and cardiovascular stress responses in 79 healthy, young men. Sleep duration was assessed by wrist actigraphy for seven nights. Participants then completed a series of laboratory stress tasks while heart rate and blood pressure were monitored. Shorter total sleep time was related to a greater reduction in high-frequency heart rate variability during stress tasks, and to prolonged elevations in heart rate and diastolic pressure following tasks. Associations were independent of age, race, body mass index, caffeine intake, and smoking status. In sum, healthy young men with shorter actigraphy-assessed sleep exhibit less cardiac vagal activity, and poorer heart rate and diastolic blood pressure recovery, upon encountering stressful stimuli, than those with longer sleep.
睡眠不足与心血管疾病的发生有关，但导致这种关系的生理机制在很大程度上尚不清楚。本研究调查了79名健康年轻男性的睡眠时间和心血管应激反应。通过手腕活动记录仪评估七个晚上的睡眠时间。参与者随后完成了一系列实验室应激任务，同时监测心率和血压。总睡眠时间较短与应激任务期间高频心率变异性的更大降低以及任务后心率和舒张压的持续升高有关。这些关联独立于年龄、种族、体重指数、咖啡因摄入量和吸烟状况。总之，与睡眠时间较长的男性相比，通过活动记录仪评估睡眠时间较短的健康年轻男性在遇到应激刺激时表现出较少的心脏迷走神经活动，以及较差的心率和舒张压恢复情况。
