Suzuki Senichi, Kobayashi Hiroyuki, Ogawa Takahiro
*Director, Lion Implant Center, Kanagawa, Japan. †Professor, Department of Hospital Administration, Juntendo University School of Medicine, Tokyo, Japan. ‡Professor, The Weintraub Center for Reconstructive Biotechnology, Division of Advanced Prosthodontics, University of California, Los Angeles, School of Dentistry, Los Angeles, CA.
Implant Dent. 2013 Oct;22(5):481-90. doi: 10.1097/ID.0b013e31829deb62.
This study evaluated the degree and rate of implant stability development for photofunctionalized dental implants in humans.
Thirty-three implants (7 patients) placed in the maxilla and immediate loaded were evaluated. Photofunctionalization was performed by treating implants with ultraviolet for 15 minutes immediately before placement. Implant stability was assessed by measuring the implant stability quotient (ISQ) weekly starting from implant placement up to 3 months. Osseointegration speed index (OSI), defined as ISQ increase per month, was also evaluated.
The average ISQ for photofunctionalized implants at week 6 was 78.0, which was considerably higher than the average ISQ of 66.1, reported in literature for various as-received implants after a longer healing time of 2 to 6 months. No stability dip was observed for photofunctionalized implants regardless of the initial ISQ values. The OSI for photofunctionalized implants was 6.3 and 3.1 when their initial ISQ was 65 to 70 and 71 to 75, respectively, whereas the OSI values for as-received implants calculated from literature ranged from -3.0 to 1.17 with an average of -0.10.
Photofunctionalization accelerated and enhanced osseointegration of dental implants, providing novel and practical avenues for further advancement in implant therapy.
本研究评估了光功能化牙种植体在人体中的植入稳定性发展程度和速率。
对33枚（7例患者）植入上颌并即刻加载的种植体进行评估。光功能化处理是在种植体植入前立即用紫外线照射15分钟。从种植体植入直至3个月，每周通过测量种植体稳定性商数（ISQ）来评估种植体稳定性。还评估了骨结合速度指数（OSI），其定义为每月ISQ的增加量。
光功能化种植体在第6周时的平均ISQ为78.0，显著高于文献报道的各种未处理种植体在愈合2至6个月更长时间后的平均ISQ 66.1。无论初始ISQ值如何，光功能化种植体均未观察到稳定性下降。当光功能化种植体的初始ISQ为65至70时，其OSI为6.3；初始ISQ为71至75时，OSI为3.1。而根据文献计算的未处理种植体的OSI值范围为 -3.0至1.17，平均为 -0.10。
光功能化加速并增强了牙种植体的骨结合，为种植治疗的进一步发展提供了新的实用途径。
