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[The effect of long-range interactions between adsorbed ligands on the DNA helix-coil transition].

作者信息

Akhrem A A, Lando D Iu, Shpakovskiĭ A G, Nechipurenko Iu D, Arutiunian S G

出版信息

Mol Biol (Mosk). 1990 May-Jun;24(3):649-56.

PMID:2402234
Abstract

The influence of different types of long-range interaction of ligands adsorbed on DNA on the helix-coil transition was theoretically considered. The contact interaction was shown to differ significantly from the long-rang one. It was shown also that even weak dependence of a long-range potential on a degree of helicity resulted in the strong changes of a DNA melting curve. This result allowed to understand the different experimental data on DNA melting in the presence of different substances which reduced AT-and GC-base pairs thermostability difference.

摘要

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