Stojadinovic Olivera, Tomic-Canic Marjana
Wound Healing and Regenerative Medicine Research Program, Department of Dermatology and Cutaneous Surgery, University of Miami Miller Medical School, Miami, FL, USA.
Methods Mol Biol. 2013;1037:255-64. doi: 10.1007/978-1-62703-505-7_14.
Wound healing is a spatially and temporally regulated process that progresses through sequential, yet overlapping phases and aims to restore barrier breach. To study this complex process scientists use various in vivo and in vitro models. Here we provide step-by-step instructions on how to perform and employ an ex vivo wound healing model to assess epithelization during wound healing in human skin.
伤口愈合是一个在空间和时间上受到调控的过程，它通过连续但相互重叠的阶段进行，旨在修复屏障破损。为了研究这个复杂的过程，科学家们使用了各种体内和体外模型。在这里，我们提供了关于如何进行和应用体外伤口愈合模型来评估人类皮肤伤口愈合过程中上皮形成的详细步骤说明。
