Universidade Federal de Minas Gerais, Departamento de Medicina Veterinária Preventiva, Laboratório de Bacteriose e Pesquisa , Belo Horizonte, MG , Brasil.
Braz J Microbiol. 2012 Jul;43(3):1030-3. doi: 10.1590/S1517-838220120003000027. Epub 2012 Jun 1.
The minimum inhibitory concentration (MIC) was determined for 13 antibiotics against Clostridium perfringens isolated from Brazilian piglets. The collection of isolates was performed in June to October 2010. All isolates were susceptible to amoxicillin and ceftiofur, whereas most were resistant to tetracycline and lincomycin. Avilamycin and narasin were more effective against isolates from non-diarrheic than from diarrheic piglets. The other antimicrobials were less active in need of high concentrations to inhibit the growth of the C. perfringens type A. These results suggest the need for further studies evaluating molecular factors related to the antimicrobial resistance of C. perfringens.
测定了从巴西仔猪中分离的 13 种抗生素对产气荚膜梭菌的最小抑菌浓度(MIC)。分离株的采集于 2010 年 6 月至 10 月进行。所有分离株均对阿莫西林和头孢噻呋敏感,而大多数对四环素和林可霉素耐药。阿维拉霉素和那拉菌素对非腹泻仔猪分离株的效果优于腹泻仔猪分离株。其他抗菌药物的活性较低,需要高浓度才能抑制 A 型产气荚膜梭菌的生长。这些结果表明需要进一步研究与产气荚膜梭菌抗菌耐药性相关的分子因素。