Gilani Gilani Rubina, Mahmood Zaid, Hussain Mushraf
Department of Chemistry, University of Engineering & Technology, Lahore, Pakistan.
Pak J Pharm Sci. 2013 Sep;26(5):893-6.
In our present research we studied physiochemical properties and antimicrobial activity of T. ammi (Trachyuspermum ammi) seeds. The seeds yielded 2.86% essential oil. Refractive index, specific gravity, acid value, and easter values were 1.496, 0.9212, 1.12 and 2.80 respectively. GLC was used to determine the composition of oil. The major component of oil was Thymol (55.308%). Antimicrobial activity of the oil was carried out against four species of bacteria and fungs. The oil was used to formulate a cream and the pH, physiochemical stability, phase separation and dermal irritation of cream were investigated. The cream was examined for healing wound in rabbits in comparison with Iodine tincture.
在我们目前的研究中，我们研究了孜然芹（藏茴香）种子的理化性质和抗菌活性。种子的精油产率为2.86%。折射率、比重、酸值和酯值分别为1.496、0.9212、1.12和2.80。采用气相色谱法测定油的成分。油的主要成分是百里香酚（55.308%）。对该油针对四种细菌和真菌进行了抗菌活性研究。该油被用于配制一种乳膏，并对乳膏的pH值、理化稳定性、相分离和皮肤刺激性进行了研究。与碘酒相比，对该乳膏在兔身上的伤口愈合情况进行了检查。
