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全身循环系统一维血液动力学中的反问题:一种序贯方法。

Inverse problems in 1D hemodynamics on systemic networks: a sequential approach.

作者信息

Lombardi D

机构信息

INRIA Paris-Rocquencourt, Domaine de Voluceau, Rocquencourt-B.P. 105, 78153 Le Chesnay, France.

出版信息

Int J Numer Method Biomed Eng. 2014 Feb;30(2):160-79. doi: 10.1002/cnm.2596. Epub 2013 Sep 9.

Abstract

In this work, a sequential approach based on the unscented Kalman filter is applied to solve inverse problems in 1D hemodynamics, on a systemic network. For instance, the arterial stiffness is estimated by exploiting cross-sectional area and mean speed observations in several locations of the arteries. The results are compared with those ones obtained by estimating the pulse wave velocity and the Moens-Korteweg formula. In the last section, a perspective concerning the identification of the terminal models parameters and peripheral circulation (modeled by a Windkessel circuit) is presented.

摘要

在这项工作中,一种基于无迹卡尔曼滤波器的序贯方法被应用于求解一维血流动力学中全身网络的逆问题。例如,通过利用动脉多个位置的横截面积和平均速度观测值来估计动脉僵硬度。将结果与通过估计脉搏波速度和门斯 - 科特韦格公式获得的结果进行比较。在最后一部分,给出了关于终端模型参数识别和外周循环(由风箱电路建模)的展望。

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