Paul Esther, Sudhagar M, Anandhalakshmi S, Mathias Shanthi
Department of Microbiology, Pondicherry Institute of Medical Sciences, Ganapthichettikulum, Kalapet, Puducherry - 605014.
Australas Med J. 2013 Aug 31;6(8):401-5. doi: 10.4066/AMJ.2013.1751. eCollection 2013.
Melioidosis is an emerging disease in India. Cases have also been reported from South East Asia, Australia and Japan. Major risk factors for melioidosis are diabetes mellitus, preexisting renal disease and thalassemia. Exposure to contaminated soil and water are also significant occupational hazards associated with the disease. A patient with diabetes of six years duration on regular medication presented with fever, generalised myalgia and headache for a week. Blood and bone marrow culture yielded Burkholderia pseudomallei. A Computed tomography (CT) study of the thorax also revealed multiple scattered nodules in both lungs. The patient was treated with imipenem and doxycycline. His condition improved gradually and he was advised oral sulfamethoxazole/trimethoprim and doxycycline for a period of three months and has been followed up regularly.
类鼻疽病在印度是一种新出现的疾病。东南亚、澳大利亚和日本也报告过病例。类鼻疽病的主要危险因素是糖尿病、既往肾病和地中海贫血。接触受污染的土壤和水也是与该疾病相关的重大职业危害。一名患有六年糖尿病且规律服药的患者出现发热、全身肌痛和头痛一周。血液和骨髓培养分离出伯克霍尔德菌。胸部计算机断层扫描（CT）检查还显示双肺有多个散在结节。该患者接受了亚胺培南和多西环素治疗。他的病情逐渐好转，并被建议口服复方磺胺甲恶唑和多西环素三个月，且已进行定期随访。
