Instituto de Química, Universidade Estadual de Campinas, C.P. 6154, 13083-970 Campinas, SP, Brasil.
Molecules. 2013 Sep 16;18(9):11429-51. doi: 10.3390/molecules180911429.
Benzoquinones are usually present in arthropod defence exudates. Here, we describe the chemical profiles of 12 harvestman species belonging to the neotropical family Gonyleptidae. Nine of the studied species produced benzoquinones, while three produced alkyl phenols. Two benzoquinones and one phenol exhibited biological activity against bacteria and fungi. We also studied the biosynthesis of 2-ethyl-1,4-benzoquinone by feeding Magnispina neptunus individuals with ¹³C-labelled precursors; the benzoquinones were biosynthesised through a polyketide pathway using acetate and propionate building blocks.
苯醌通常存在于节肢动物防御分泌物中。在这里，我们描述了 12 种属于新热带 Gonyleptidae 科的蜘蛛物种的化学特征。在所研究的 12 种物种中，有 9 种产生了苯醌，而有 3 种产生了烷基酚。两种苯醌和一种苯酚对细菌和真菌表现出生物活性。我们还通过用¹³C 标记的前体喂养 Magnispina neptunus 个体来研究 2-乙基-1,4-苯醌的生物合成；苯醌通过使用乙酸盐和丙酸盐构建块的聚酮途径生物合成。
