Lin Pao-Hwa, Yeh Wen-Ting, Svetkey Laura P, Chuang Shao-Yuan, Chang Yuan-Chin, Wang Christine, Pan Wen-Harn
Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Asia Pac J Clin Nutr. 2013;22(3):482-91.
The Dietary Approaches to Stop Hypertension (DASH) diet has been proven to effectively lower blood pressure(BP), and associate with a lower cardiovascular disease and stroke risk in mainly non-Asians. Further, it is unclear if adhering to the DASH target nutrients has similar BP impact as adhering to the recommended DASH food groups. Associations between adherence to DASH foods or nutrients and BP or stroke risk were assessed in 1420 and 2061 Taiwanese adults from 1989 to 2002, respectively. The DASH food score (p=0.053), dairy(p=0.030) and calcium (p=0.020) intake were significantly and inversely associated with follow up systolic BP change in univariate analyses. Both dairy (p=0.020) and calcium (p=0.001) also showed a consistent inverse association with systolic BP change in multivariate analysis. None of the factors examined was associated with diastolic BP change. Both DASH nutrient score and magnesium intakes were significantly associated with the hazard ratio (HR) for total stroke in an inverse relationship. The HR of total stroke comparing the highest to the lowest tertile was 0.63 (95% CI: 0.41-0.98, p=0.037) for the DASH nutrient score, and 0.62 (95% CI: 0.40-0.97,p=0.030) for magnesium intake. Similar findings were observed for DASH nutrient score (p=0.011) and magnesium intake (p=0.043) with the HR for ischemic stroke. The HR for total and ischemic stroke for calcium intake also showed a borderline trend (p=0.071 and 0.051, respectively). In conclusion, adhering to the DASH diet is beneficial for long term BP control and reduction of stroke risk in this Chinese population.
已证实,停止高血压膳食疗法(DASH饮食法)能有效降低血压(BP),并且在主要为非亚洲人群中,与较低的心血管疾病和中风风险相关。此外,尚不清楚坚持DASH目标营养素与坚持推荐的DASH食物组对血压的影响是否相似。分别在1989年至2002年期间,对1420名和2061名台湾成年人进行了研究,评估坚持DASH食物或营养素与血压或中风风险之间的关联。在单因素分析中,DASH食物评分(p=0.053)、乳制品摄入量(p=0.030)和钙摄入量(p=0.020)与随访期间收缩压变化呈显著负相关。在多因素分析中,乳制品(p=0.020)和钙(p=0.001)与收缩压变化也呈现一致的负相关。所研究的因素均与舒张压变化无关。DASH营养素评分和镁摄入量均与总中风风险比(HR)呈显著负相关。DASH营养素评分方面,总中风风险比最高三分位数与最低三分位数相比为0.63(95%置信区间:0.41-0.98,p=0.037),镁摄入量方面为0.62(95%置信区间:0.40-0.97,p=0.030)。对于缺血性中风的风险比,DASH营养素评分(p=0.011)和镁摄入量(p=0.043)也有类似发现。钙摄入量的总中风和缺血性中风风险比也呈现临界趋势(分别为p=0.071和0.051)。总之,坚持DASH饮食法对该中国人群的长期血压控制和降低中风风险有益。