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实现癌症基因组图谱中 12 种肿瘤类型的透明和协作计算分析。

Enabling transparent and collaborative computational analysis of 12 tumor types within The Cancer Genome Atlas.

机构信息

1] Sage Bionetworks, Seattle, Washington, USA. [2].

出版信息

Nat Genet. 2013 Oct;45(10):1121-6. doi: 10.1038/ng.2761.

DOI:10.1038/ng.2761
PMID:24071850
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3950337/
Abstract

The Cancer Genome Atlas Pan-Cancer Analysis Working Group collaborated on the Synapse software platform to share and evolve data, results and methodologies while performing integrative analysis of molecular profiling data from 12 tumor types. The group's work serves as a pilot case study that provides (i) a template for future large collaborative studies; (ii) a system to support collaborative projects; and (iii) a public resource of highly curated data, results and automated systems for the evaluation of community-developed models.

摘要

癌症基因组图谱泛癌症分析工作组在 Synapse 软件平台上合作,共享和发展数据、结果和方法,同时对来自 12 种肿瘤类型的分子分析数据进行综合分析。该工作组的工作是一个试点案例研究,提供了 (i) 未来大型合作研究的模板;(ii) 支持合作项目的系统;以及 (iii) 经过高度编辑的数据、结果和自动化系统的公共资源,用于评估社区开发的模型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5843/3950337/babe21f8f666/nihms554182f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5843/3950337/0307449a4c56/nihms554182f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5843/3950337/12dd3e29a6a3/nihms554182f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5843/3950337/babe21f8f666/nihms554182f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5843/3950337/0307449a4c56/nihms554182f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5843/3950337/12dd3e29a6a3/nihms554182f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5843/3950337/babe21f8f666/nihms554182f3.jpg

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