膀胱癌的诊断年龄：鸦片成瘾起作用吗？
Age at diagnosis in bladder cancer: does opium addiction play a role?
作者信息
Karbakhsh Mojgan, Dabbagh Najmeh, Shabani Azadeh, Tabibi Ali, Akhavizadegan Hamed
机构信息
Community and Preventive Medicine Department, Tehran University of Medical Sciences, Tehran, Iran E-mail :
出版信息
Asian Pac J Cancer Prev. 2013;14(8):4723-5. doi: 10.7314/apjcp.2013.14.8.4723.
BACKGROUND
Bladder cancer is a major health problem, especially among men. Opium addiction can be an important risk factor. One important question is whether it can affect the age of onset of bladder cancer .We performed this study to evaluate this question.
MATERIALS AND METHODS
In a cross-section study, records of patients diagnosed with bladder carcinoma in Shahid Labbafinejad Medical Center, within 1999-2008 were included. Data were extracted from records regarding age at onset, gender, smoking status, and opioid addiction and analyzed with SPSS 13.
RESULTS
Within 10 years, 920 cases were diagnosed with bladder cancer of which 97 percent were transitional cell carcinoma. In 698 cases, opium addiction status was recorded in 21.3% (n=149). Age at diagnosis was 59.7±11.51 (median: 60) among opioid addicts which was significantly lower than non- addicts (63.1±13.65, Median: 65) (P<0.001).
CONCLUSIONS
Opium addiction can decrease the age of onset of bladder cancer.
背景
膀胱癌是一个主要的健康问题，尤其是在男性中。鸦片成瘾可能是一个重要的风险因素。一个重要的问题是它是否会影响膀胱癌的发病年龄。我们进行这项研究以评估这个问题。
材料与方法
在一项横断面研究中，纳入了1999年至2008年期间在沙希德·拉巴菲内贾德医疗中心被诊断为膀胱癌的患者记录。从记录中提取有关发病年龄、性别、吸烟状况和阿片类药物成瘾的数据，并使用SPSS 13进行分析。
结果
在10年期间，920例被诊断为膀胱癌，其中97%为移行细胞癌。在698例病例中，记录了鸦片成瘾状况，占21.3%（n = 149）。阿片类药物成瘾者的诊断年龄为59.7±11.51（中位数：60），显著低于非成瘾者（63.1±13.65，中位数：65）（P<0.001）。
结论
鸦片成瘾会降低膀胱癌的发病年龄。
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