Casswell A G, Kohen D, Bird A C
Br J Ophthalmol. 1985 Jun;69(6):397-403. doi: 10.1136/bjo.69.6.397.
Sixty-four eyes of 57 elderly patients with pigment epithelial detachments (PEDs) were studied with the aim of describing their morphological features and identifying prognostic factors. They were classified into four groups according to the following characteristics: early fluorescence, late fluorescence, shallow detachment with limited fluorescence ('drusen type'), irregular fluorescence. The following conclusions were drawn: 30% developed demonstrable subretinal new vessels; all groups except the drusen type were susceptible, the irregular group being particularly prone. 10% developed retinal pigment epithelial tears, and these occurred almost exclusively in the slow fluorescent group. Flattening of PEDs was a feature of drusen type and early fluorescent groups. Most patients lost vision. RPE tears occurred within a few months of presentation with immediate loss of vision; likewise rapid loss of vision followed the development of demonstrable new vessels, though not necessarily in those with changes thought to imply the presence of new vessels. Flattening after prolonged detachment was associated with pigment epithelial atrophy and invariable loss of vision. Visual acuity was maintained consistently only in those eyes with persistent detachment.
对57例患有色素上皮脱离(PED)的老年患者的64只眼睛进行了研究,目的是描述其形态特征并确定预后因素。根据以下特征将它们分为四组:早期荧光、晚期荧光、伴有有限荧光的浅脱离(“玻璃疣型”)、不规则荧光。得出以下结论:30%出现了可证实的视网膜下新生血管;除玻璃疣型外的所有组都易患,不规则组尤其容易发生。10%出现了视网膜色素上皮撕裂,且几乎都发生在慢荧光组。PED的扁平是玻璃疣型和早期荧光组的一个特征。大多数患者视力下降。RPE撕裂在就诊后几个月内发生,视力立即丧失;同样,可证实的新生血管形成后视力迅速下降,不过不一定发生在那些有被认为意味着存在新生血管的改变的患者身上。长期脱离后的扁平与色素上皮萎缩和视力的不可避免丧失有关。仅在那些持续脱离的眼睛中视力得以持续维持。