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脊髓损伤中压疮的综合管理:当前概念与未来趋势。

Comprehensive management of pressure ulcers in spinal cord injury: current concepts and future trends.

作者信息

Kruger Erwin A, Pires Marilyn, Ngann Yvette, Sterling Michelle, Rubayi Salah

机构信息

Department of Surgery, Pressure Ulcer Management Service, Rancho Los Amigos National Rehabilitation Center, Downey, CA, USA.

Department of Nursing, Rancho Los Amigos National Rehabilitation Center, Downey, CA, USA.

出版信息

J Spinal Cord Med. 2013 Nov;36(6):572-85. doi: 10.1179/2045772313Y.0000000093. Epub 2013 May 21.

DOI:10.1179/2045772313Y.0000000093
PMID:24090179
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3831318/
Abstract

Pressure ulcers in spinal cord injury represent a challenging problem for patients, their caregivers, and their physicians. They often lead to recurrent hospitalizations, multiple surgeries, and potentially devastating complications. They present a significant cost to the healthcare system, they require a multidisciplinary team approach to manage well, and outcomes directly depend on patients' education, prevention, and compliance with conservative and surgical protocols. With so many factors involved in the successful treatment of pressure ulcers, an update on their comprehensive management in spinal cord injury is warranted. Current concepts of local wound care, surgical options, as well as future trends from the latest wound healing research are reviewed to aid medical professionals in treating patients with this difficult problem.

摘要

脊髓损伤患者的压疮对患者本人、其护理人员及其医生来说都是一个具有挑战性的问题。它们常常导致反复住院、多次手术以及可能带来毁灭性的并发症。它们给医疗系统带来了巨大的成本,需要多学科团队协作才能妥善管理,而且治疗结果直接取决于患者的教育程度、预防措施以及对保守和手术方案的依从性。由于成功治疗压疮涉及诸多因素,因此有必要对脊髓损伤患者压疮的综合管理进行更新。本文回顾了局部伤口护理的当前理念、手术选择以及最新伤口愈合研究的未来趋势,以帮助医疗专业人员治疗患有这一难题的患者。

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本文引用的文献

1
An evidence-based approach to the surgical management of pressure ulcers.压力性溃疡手术治疗的循证医学方法。
Ann Plast Surg. 2012 Oct;69(4):482-4. doi: 10.1097/SAP.0b013e31824b26bc.
2
A systematic review of complication and recurrence rates of musculocutaneous, fasciocutaneous, and perforator-based flaps for treatment of pressure sores.肌皮瓣、筋膜皮瓣和穿支皮瓣治疗压疮的并发症和复发率的系统评价。
Plast Reconstr Surg. 2012 Jul;130(1):67e-77e. doi: 10.1097/PRS.0b013e318254b19f.
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Directed migration of human bone marrow mesenchymal stem cells in a physiological direct current electric field.生理直流电场中人类骨髓间充质干细胞的定向迁移。
Eur Cell Mater. 2011 Nov 29;22:344-58. doi: 10.22203/ecm.v022a26.
4
Mesenchymal stem cell therapy and delivery systems in nonhealing wounds.间充质干细胞治疗与非愈合性创面的输送系统。
Adv Skin Wound Care. 2011 Nov;24(11):524-32; quiz 533-4. doi: 10.1097/01.ASW.0000407648.89961.a6.
5
Trunk, abdomen, and pressure sore reconstruction.躯干、腹部和压疮重建。
Plast Reconstr Surg. 2011 Sep;128(3):201e-215e. doi: 10.1097/PRS.0b013e31822214c1.
6
Degenerate wave and capacitive coupling increase human MSC invasion and proliferation while reducing cytotoxicity in an in vitro wound healing model.退变波和电容耦合增加人 MSC 侵袭和增殖,同时减少体外愈合模型中的细胞毒性。
PLoS One. 2011;6(8):e23404. doi: 10.1371/journal.pone.0023404. Epub 2011 Aug 16.
7
Treatment of pressure ulcers with autologous bone marrow nuclear cells in patients with spinal cord injury.脊髓损伤患者自体骨髓核细胞治疗压疮
J Spinal Cord Med. 2011;34(3):301-7. doi: 10.1179/2045772311Y.0000000010.
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Association of race and sites of care with pressure ulcers in high-risk nursing home residents.种族和护理场所与高风险养老院居民压疮的关系。
JAMA. 2011 Jul 13;306(2):179-86. doi: 10.1001/jama.2011.942.
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Support surfaces for pressure ulcer prevention.预防压疮的支撑面
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Pressure ulcers: avoidable or unavoidable? Results of the National Pressure Ulcer Advisory Panel Consensus Conference.压疮:可避免还是不可避免?国家压疮咨询小组共识会议的结果
Ostomy Wound Manage. 2011 Feb;57(2):24-37.