正常认知老化。
Normal cognitive aging.
机构信息
Geriatrics Research, Education, and Clinical Center, Birmingham Veterans Affairs Medical Center; Division of Gerontology, Geriatrics, and Palliative Care, University of Alabama at Birmingham, CH-19-201, 1720 Second Avenue South, Birmingham, AL 35294, USA.
出版信息
Clin Geriatr Med. 2013 Nov;29(4):737-52. doi: 10.1016/j.cger.2013.07.002.
Abstract
Even those who do not experience dementia or mild cognitive impairment may experience subtle cognitive changes associated with aging. Normal cognitive changes can affect an older adult's everyday function and quality of life, and a better understanding of this process may help clinicians distinguish normal from disease states. This article describes the neurocognitive changes observed in normal aging, followed by a description of the structural and functional alterations seen in aging brains. Practical implications of normal cognitive aging are then discussed, followed by a discussion of what is known about factors that may mitigate age-associated cognitive decline.
摘要
即使那些没有经历痴呆或轻度认知障碍的人，也可能会经历与衰老相关的微妙认知变化。正常的认知变化会影响老年人的日常生活功能和生活质量，更好地了解这一过程可能有助于临床医生区分正常状态和疾病状态。本文描述了正常衰老过程中观察到的神经认知变化，接着描述了衰老大脑中观察到的结构和功能改变。然后讨论了正常认知衰老的实际意义，接着讨论了已知的可能减轻与年龄相关的认知衰退的因素。
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