Center for Genomic Sciences, United States Army Medical Research Institute for Infectious Diseases, Frederick, MD, USA.
Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.
J Gen Virol. 2014 Feb;95(Pt 2):292-300. doi: 10.1099/vir.0.056614-0. Epub 2013 Oct 4.
Genomic and antigenic characterization of members of the Sandfly fever Naples virus (SFNV) complex reveals the presence of five clades that differ in their geographical distribution. Saint Floris and Gordil viruses, both found in Africa, form one clade; Punique, Granada and Massilia viruses, all isolated in the western Mediterranean, constitute a second; Toscana virus, a third; SFNV isolates from Italy, Cyprus, Egypt and India form a fourth; while Tehran virus and a Serbian isolate Yu 8/76, represent a fifth. Interestingly, this last clade appears not to express the second non-structural protein ORF. Karimabad virus, previously classified as a member of the SFNV complex, and Gabek Forest virus are distinct and form a new species complex (named Karimabad) in the Phlebovirus genus. In contrast with the high reassortment frequency observed in some South American phleboviruses, the only virus of the SFNV complex with evidence of reassortment was Granada virus.
沙蝇热那不勒斯病毒（SFNV）复合体成员的基因组和抗原特征表明，存在五个在地理分布上不同的分支。均在非洲发现的圣弗洛里斯病毒和戈尔迪尔病毒形成一个分支；普尼克病毒、格拉纳达病毒和马西利亚病毒均在西地中海地区分离到，构成第二个分支；托斯卡纳病毒构成第三个分支；来自意大利、塞浦路斯、埃及和印度的 SFNV 分离株构成第四个分支；而德黑兰病毒和塞尔维亚的 Yu 8/76 分离株代表第五个分支。有趣的是，最后一个分支似乎不表达第二个非结构蛋白 ORF。卡里马巴德病毒以前被归类为 SFNV 复合体的成员，而加贝克森林病毒是不同的，并在黄病毒属中形成了一个新的种复合体（命名为卡里马巴德）。与在一些南美洲黄病毒中观察到的高重配频率相反，SFNV 复合体中唯一有重配证据的病毒是格拉纳达病毒。
