Spyratos Dionysios, Zarogoulidis Paul, Porpodis Konstantinos, Tsakiridis Kosmas, Machairiotis Nikolaos, Katsikogiannis Nikolaos, Kougioumtzi Ioanna, Dryllis Georgios, Kallianos Anastasios, Rapti Aggeliki, Li Chen, Zarogoulidis Konstantinos
Pulmonary Department-Oncology Unit, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece;
J Thorac Dis. 2013 Sep;5 Suppl 4(Suppl 4):S440-5. doi: 10.3978/j.issn.2072-1439.2013.07.09.
Lung cancer is the leading cause of cancer death for male and the second most usual cancer for women after breast cancer. Currently there are available several non-specific cytotoxic agents and several targeted agents for lung cancer therapy. However; early stage diagnosis is still unavailable and several efforts are being made towards this direction. Novel biomarkers are being investigated along with new biopsy techniques. The occupational and environmental exposure to carcinogenic agents is an everyday phenomenon. Therefore until efficient early diagnosis is available, avoidance of exposure to carcinogenic agents is necessary. In the current mini-review occupational and environmental carcinogenic agents will be presented.
肺癌是男性癌症死亡的主要原因，也是女性仅次于乳腺癌的第二大常见癌症。目前有几种用于肺癌治疗的非特异性细胞毒性药物和几种靶向药物。然而，早期诊断仍然无法实现，目前正朝着这个方向做出多项努力。新型生物标志物以及新的活检技术正在研究中。职业和环境中接触致癌物质是日常现象。因此，在获得有效的早期诊断之前，避免接触致癌物质是必要的。在本小型综述中，将介绍职业和环境致癌物质。
