Zheng Yali, Yan Bryan P, Zhang Yuanting, Yu C M, Poon Carmen C Y
Annu Int Conf IEEE Eng Med Biol Soc. 2013;2013:6103-6. doi: 10.1109/EMBC.2013.6610945.
A wearable cuff-less pulse transit time (PTT) based monitoring device is developed for ambulatory blood pressure (BP) monitoring. Ten healthy subjects (aged 27 ± 4 years old) underwent 24-hour ambulatory BP monitoring using 1) a standard brachial cuff-based oscillometric device as reference and 2) the proposed cuff-less PTT measuring system. Raw PTT and BP measurements were linearly interpolated and then smoothed by a low-pass filter to remove aliasing effect caused by the low sampling rate and synchronized. Resampled PTT and BP were assessed for correlation using correlation coefficients and Bland-Altman plots. Our study showed that PTT estimated systolic BP most accurately within 4.8 ± 4.3 mmHg on healthy young subjects during sleep time. We conclude from this study that the proposed cuff-less PTT-based BP monitoring system has potential to be a less intrusive alternative to standard oscillometric method for long-term overnight BP monitoring.
一种基于可穿戴无袖脉搏传输时间（PTT）的监测设备被开发用于动态血压（BP）监测。十名健康受试者（年龄27±4岁）接受了24小时动态血压监测，使用1）基于标准肱动脉袖带的示波测量设备作为参考，以及2）所提出的无袖PTT测量系统。对原始PTT和血压测量值进行线性插值，然后通过低通滤波器进行平滑处理，以消除低采样率引起的混叠效应并进行同步。使用相关系数和布兰德-奥特曼图评估重新采样的PTT和血压之间的相关性。我们的研究表明，在睡眠时间，PTT对健康年轻受试者收缩压的估计最为准确，误差在4.8±4.3 mmHg以内。我们从这项研究中得出结论，所提出的基于无袖PTT的血压监测系统有可能成为标准示波法用于长期夜间血压监测的侵入性较小的替代方法。
