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Harvest:一个用于开发基于网络的生物医学数据发现和报告应用程序的开放平台。

Harvest: an open platform for developing web-based biomedical data discovery and reporting applications.

机构信息

Center for Biomedical Informatics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

出版信息

J Am Med Inform Assoc. 2014 Mar-Apr;21(2):379-83. doi: 10.1136/amiajnl-2013-001825. Epub 2013 Oct 16.

Abstract

Biomedical researchers share a common challenge of making complex data understandable and accessible as they seek inherent relationships between attributes in disparate data types. Data discovery in this context is limited by a lack of query systems that efficiently show relationships between individual variables, but without the need to navigate underlying data models. We have addressed this need by developing Harvest, an open-source framework of modular components, and using it for the rapid development and deployment of custom data discovery software applications. Harvest incorporates visualizations of highly dimensional data in a web-based interface that promotes rapid exploration and export of any type of biomedical information, without exposing researchers to underlying data models. We evaluated Harvest with two cases: clinical data from pediatric cardiology and demonstration data from the OpenMRS project. Harvest's architecture and public open-source code offer a set of rapid application development tools to build data discovery applications for domain-specific biomedical data repositories. All resources, including the OpenMRS demonstration, can be found at http://harvest.research.chop.edu.

摘要

生物医学研究人员面临着一个共同的挑战,即如何在不同数据类型之间寻找属性之间的内在关系,从而使复杂的数据变得易于理解和访问。在这种情况下,数据发现受到缺乏高效显示单个变量之间关系的查询系统的限制,但又不需要导航底层数据模型。我们通过开发 Harvest 来满足这一需求,这是一个开源的模块化组件框架,并使用它快速开发和部署自定义数据发现软件应用程序。Harvest 在基于网络的界面中可视化高维数据,促进快速探索和导出任何类型的生物医学信息,而不会让研究人员接触到底层数据模型。我们用两个案例评估了 Harvest:儿科心脏病学的临床数据和 OpenMRS 项目的演示数据。Harvest 的架构和公共开源代码为构建特定于领域的生物医学数据存储库的数据发现应用程序提供了一组快速应用程序开发工具。所有资源,包括 OpenMRS 演示,都可以在 http://harvest.research.chop.edu 找到。

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