Medvedev D I, Babichenko I I, Kravtsova A I, Eremina I Z
Biull Eksp Biol Med. 1985 Nov;100(11):617-20.
Quantitative analysis has been carried out on semithin sections of cerebellum cortex to investigate the relation between Purkinje cells with different dyeing properties. The number of dark Purkinje cells was found to increase after a month-long food rehabilitation of ill-fed mice. At the same time addition of carnitine to the mouse food has resulted in a significant decline in the number of dark Purkinje cells, as compared to control animals. The data obtained suggest that the rising number of dark Purkinje cells in the cerebellum cortex under conditions of malnutrition is probably due to the increased intracellular accumulation of free fatty acids.
已对小脑皮质的半薄切片进行定量分析，以研究具有不同染色特性的浦肯野细胞之间的关系。发现长期营养不良的小鼠经过一个月的食物恢复后，深色浦肯野细胞的数量增加。同时，与对照动物相比，在小鼠食物中添加肉碱导致深色浦肯野细胞数量显著下降。所获得的数据表明，营养不良条件下小脑皮质中深色浦肯野细胞数量的增加可能是由于细胞内游离脂肪酸积累增加所致。
