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[蛋白质 - 热量缺乏对发育中和成年动物小脑皮质分子层突触超微结构的影响]

[Effect of protein-calorie deficiency on the ultrastructure of synapses in the molecular layer of the cerebellar cortex in developing and adult animals].

作者信息

Medvedev D I, Babichenko I I, Kravtsova A I, Eremina I Z

出版信息

Biull Eksp Biol Med. 1988 Jul;106(7):106-8.

PMID:3135854
Abstract

The influence of protein-caloric deficiency on the ultrastructure of synapses in the molecular layer of the cerebellum has been quantitatively assessed in young and adult mice. It has been found that protein-caloric deficiency in the early postnatal period delays the time of axo-dendritic synapse development in the neuropil. Adult mice were more resistant to the influence of protein-caloric deficiency because of an increase in compensatory-adaptive reactions found in the cerebellum.

摘要

在幼年和成年小鼠中,已对蛋白质 - 热量缺乏对小脑分子层突触超微结构的影响进行了定量评估。研究发现,出生后早期的蛋白质 - 热量缺乏会延迟神经毡中轴突 - 树突突触的发育时间。成年小鼠对蛋白质 - 热量缺乏的影响更具抵抗力,这是因为在小脑中发现了代偿性 - 适应性反应的增加。

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