Department of Dental Materials and Biomaterials Research, RWTH Aachen University Hospital, Pauwelsstrasse 30, 52074 Aachen, Germany.
Dent Mater. 2013 Dec;29(12):1256-64. doi: 10.1016/j.dental.2013.09.016. Epub 2013 Oct 21.
Amorphous bioglass 45S5 has been used for many years as bone substitute material. Bioactive glasses are also suitable as coating materials for implants in order to improve the bone ongrowth behavior. We hypothesize that both the apatite formation on the surface and the chemical stability can be improved by crystallization of the bioglass.
Synthesized amorphous bioglass 45S5 specimens as well as samples which were crystallized at 1000 °C were stored in simulated body fluid for 1, 7, and 14 days. The respective apatite formation was gravimetrically determined and characterized by SEM and XRD analysis. Moreover, the degradation behavior was studied after storage in distilled water.
The weight of the crystallized samples decreased 6.3% less than that of the amorphous samples. Calcium silica and calcium carbonate layers were found on amorphous bioglass after 7 and 14 days. However, apatite formation was observed only on the crystallized 45S5 samples after storage.
We conclude that the chemical resistance can be improved and, in parallel, a pronounced apatite formation on the surface of 45S5 can be obtained by controlled crystallization of the material for the particular test setup. Therefore, crystallized bioactive glasses should be considered to be promising coating material for dental implants.
非晶态生物玻璃 45S5 多年来一直被用作骨替代材料。生物活性玻璃也适合用作植入物的涂层材料，以改善骨长入行为。我们假设通过玻璃的结晶可以改善表面上的磷灰石形成和化学稳定性。
合成的非晶态生物玻璃 45S5 标本以及在 1000°C 下结晶的样品在模拟体液中储存 1、7 和 14 天。通过重量法分别确定各自的磷灰石形成，并通过 SEM 和 XRD 分析进行表征。此外，还研究了在蒸馏水中储存后的降解行为。
结晶样品的重量比非晶样品减少了 6.3%。在非晶态生物玻璃上，在 7 天和 14 天后发现了钙硅和碳酸钙层。然而，仅在储存后观察到结晶 45S5 样品表面形成磷灰石。
我们得出结论，通过控制材料的结晶，可以提高耐化学性，并在特定的测试设置中获得表面上明显的磷灰石形成。因此，结晶生物活性玻璃应被认为是有前途的牙科植入物涂层材料。
