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载氧化铁的中空介孔硅纳米胶囊用于控制药物释放和热疗。

Iron oxide-loaded hollow mesoporous silica nanocapsules for controlled drug release and hyperthermia.

机构信息

Department of Chemistry, Case Western Reserve University, 10900 Euclid Ave., Cleveland, OH 44106, USA.

出版信息

Chem Commun (Camb). 2013 Dec 18;49(97):11436-8. doi: 10.1039/c3cc46658b.

DOI:10.1039/c3cc46658b
PMID:24169596
Abstract

Magnetic field-responsive iron oxide-loaded hollow mesoporous silica nanocapsules that exhibit high drug loading capacity were synthesized using polymer nanospheres as sacrificial templates. Due to their magnetic field induced heating and remotely triggered drug release capabilities, these hybrid nanomaterials provide an excellent platform for the combination of hyperthermia and chemotherapy.

摘要

采用聚合物纳米球作为牺牲模板，合成了具有高载药能力的磁场响应型载氧化铁的中空介孔硅纳米胶囊。由于其磁场诱导加热和远程触发药物释放的能力，这些杂化纳米材料为热疗和化疗的联合提供了一个极好的平台。

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