多通道原子磁力计用于脑磁图：一种配置研究。

Multi-channel atomic magnetometer for magnetoencephalography: a configuration study.

机构信息

Korea Research Institute of Standards and Science, South Korea.

Faculty of Electrical Engineering, Ljubljana, Slovenia.

出版信息

Neuroimage. 2014 Apr 1;89:143-51. doi: 10.1016/j.neuroimage.2013.10.040. Epub 2013 Nov 1.

DOI:10.1016/j.neuroimage.2013.10.040

PMID:24185014

Abstract

Atomic magnetometers are emerging as an alternative to SQUID magnetometers for detection of biological magnetic fields. They have been used to measure both the magnetocardiography (MCG) and magnetoencephalography (MEG) signals. One of the virtues of the atomic magnetometers is their ability to operate as a multi-channel detector while using many common elements. Here we study two configurations of such a multi-channel atomic magnetometer optimized for MEG detection. We describe measurements of auditory evoked fields (AEF) from a human brain as well as localization of dipolar phantoms and auditory evoked fields. A clear N100m peak in AEF was observed with a signal-to-noise ratio of higher than 10 after averaging of 250 stimuli. Currently the intrinsic magnetic noise level is 4fTHz(-1/2) at 10Hz. We compare the performance of the two systems in regards to current source localization and discuss future development of atomic MEG systems.

摘要

原子磁力计作为超导量子干涉磁力计（SQUID）的替代品，正在成为生物磁场检测的一种选择。它们已被用于测量心磁图（MCG）和脑磁图（MEG）信号。原子磁力计的一个优点是，它们能够在使用许多常见元件的情况下作为多通道探测器运行。在这里，我们研究了两种针对 MEG 检测进行优化的这种多通道原子磁力计的配置。我们描述了从人脑测量听觉诱发场（AEF），以及对偶极子幻影和听觉诱发场的定位。在对 250 个刺激进行平均后，观察到 AEF 中出现了明显的 N100m 峰值，信噪比高于 10。目前，在 10Hz 时，固有磁噪声水平为 4fTHz(-1/2)。我们比较了这两个系统在电流源定位方面的性能，并讨论了原子 MEG 系统的未来发展。