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1型单纯疱疹病毒经父亲垂直传播致新生儿暴发性肝炎

Fulminant Hepatitis Due to Father-to-Newborn Transmission of Herpes Simplex Virus type 1.

作者信息

Bal A, Zandotti C, Nougairede A, Ninove L, Roquelaure B, Charrel R N

机构信息

IHU Mediterranee Infection, APHM Public Hospitals of Marseille, 13005 Marseille, France.

出版信息

Open Virol J. 2013 Oct 31;7:96-7. doi: 10.2174/1874357901307010096. eCollection 2013.

Abstract

We describe a case of a severe neonatal infection by herpes simplex virus (HSV) type 1 acquired postnatally from his father. The delivery and the first days of life were normal. He developed liver failure and disseminated intravascular coagulation when he was 19 days old. He was treated with intravenous acyclovir and the outcome was favorable. This case underlines that prevention of post-natal transmission of HSV merits to be considered in educational pregnancy programs directed at mothers and fathers.

摘要

我们描述了一例1型单纯疱疹病毒(HSV)引起的严重新生儿感染病例,该感染是新生儿出生后从其父亲那里获得的。分娩过程及出生后的头几天均正常。患儿19日龄时出现肝衰竭和弥散性血管内凝血。他接受了静脉注射阿昔洛韦治疗,结果良好。该病例强调,在针对准父母的孕期教育项目中,应考虑预防HSV的产后传播。

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本文引用的文献

1
Herpes simplex virus infections in preterm infants.早产儿的单纯疱疹病毒感染
Pediatrics. 2006 Dec;118(6):e1612-20. doi: 10.1542/peds.2005-1228.
2
Herpes simplex virus infections in neonates and early childhood.新生儿和幼儿的单纯疱疹病毒感染
Semin Pediatr Infect Dis. 2005 Oct;16(4):271-81. doi: 10.1053/j.spid.2005.06.007.
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Neonatal herpes simplex infection.新生儿单纯疱疹感染
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Detection of Herpes simplex virus DNA by real-time PCR.通过实时聚合酶链反应检测单纯疱疹病毒DNA
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Transmission of herpes simplex virus from father to neonate.
J Pediatr. 1983 Dec;103(6):905-7. doi: 10.1016/s0022-3476(83)80710-0.

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