两个与干扰素共同诱导的小鼠基因定位于12号染色体和X染色体

Assignment of two mouse genes coinduced with interferon to chromosomes 12 and X.

作者信息

Kelley K A, Pitha P M, Demaeyer-Guignard J, Demaeyer E, Kozak C

出版信息

J Interferon Res. 1986 Feb;6(1):51-7. doi: 10.1089/jir.1986.6.51.

DOI:10.1089/jir.1986.6.51

Abstract

Two murine cDNAs (pMIF20/11 and pMIF3/10) coinduced with interferon in mouse cells infected with Newcastle disease virus (NDV) were identified previously. By genomic Southern blot analysis of hamster/mouse somatic cell hybrids, the gene hybridizing with pMIF20/11 has been localized on chromosome 12 and the gene hybridizing with pMIF3/10 on chromosome X.

摘要

先前已鉴定出在感染新城疫病毒（NDV）的小鼠细胞中与干扰素共同诱导产生的两个小鼠cDNA（pMIF20/11和pMIF3/10）。通过对仓鼠/小鼠体细胞杂种进行基因组Southern印迹分析，与pMIF20/11杂交的基因已定位在12号染色体上，与pMIF3/10杂交的基因定位在X染色体上。