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慢性荨麻疹:印度背景下的挑战与治疗选择

Chronic urticaria: Indian context-challenges and treatment options.

作者信息

Khan Sujoy, Maitra Anirban, Hissaria Pravin, Roy Sitesh, Padukudru Anand Mahesh, Nag Nalin, Singh Harpal

机构信息

Consultant Allergist & Immunologist, Department of Allergy & Immunology, Apollo Gleneagles Hospital, 58 Canal Circular Road, Kolkata, West Bengal 700 054, India.

出版信息

Dermatol Res Pract. 2013;2013:651737. doi: 10.1155/2013/651737. Epub 2013 Sep 24.

Abstract

Urticaria is a common condition that occurs in both children and adults. Most cases have no specific allergic trigger and the aetiology of urticaria remains idiopathic and occasionally spontaneous in nature. Inappropriate advice such as avoidance of foods (milk, egg, prawn, and brinjal) is common place in certain sections of India mostly by nonspecialists that should not be routinely recommended. It is important to look for physical urticarias such as pressure urticaria in chronic cases, which may be present either alone or in combination with other causes. Autoimmune causes for chronic urticaria have been found to play an important role in a significant proportion of patients. Long-acting nonsedating antihistamines at higher than the standard doses is safe and effective. Quality of life is affected adversely in patients with chronic symptomatic urticaria and some may require multidisciplinary management.

摘要

荨麻疹是一种常见病症,在儿童和成人中均有发生。大多数病例没有特定的过敏触发因素,荨麻疹的病因仍然是特发性的,偶尔本质上是自发性的。在印度的某些地区,非专科医生经常给出不恰当的建议,如避免食用某些食物(牛奶、鸡蛋、虾和茄子),而这些建议不应被常规推荐。对于慢性荨麻疹病例,重要的是要排查物理性荨麻疹,如压力性荨麻疹,其可能单独出现或与其他病因同时存在。已发现自身免疫性病因在相当一部分慢性荨麻疹患者中起重要作用。高于标准剂量的长效非镇静抗组胺药是安全有效的。慢性症状性荨麻疹患者的生活质量会受到不利影响,部分患者可能需要多学科管理。

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