Sánchez-Borges Mario, González-Aveledo Luis, Caballero-Fonseca Fernan, Capriles-Hulett Arnaldo
Allergy and Clinical Immunology Department, Centro Médico Docente La Trinidad, Caracas, Venezuela.
Allergy and Clinical Immunology Service, Clínica El Avila, 6a transversal Urb. Altamira, piso 8, consultorio 803, Caracas, 1060, Venezuela.
Curr Allergy Asthma Rep. 2017 Aug;17(8):51. doi: 10.1007/s11882-017-0722-1.
This review aims to update the information available on the prevalence, clinical picture, diagnostic methods, and treatment of urticarias induced by external physical stimuli.
Physical urticarias are present in up to 5% of the general population, and in 10 to 50% of patients with chronic urticaria. Recent investigations have provided evidence that the presence of physical urticaria alone or when comorbid with chronic spontaneous urticaria is associated with a worse prognosis and duration. Most frequent subtypes of physical urticaria are dermographism and delayed pressure urticaria. The diagnosis is established through specific provocation tests and the management encompasses avoidance measures, pharmacologic therapy with nonsedating antihistamines, and alternative medications in refractory cases.
本综述旨在更新有关外部物理刺激诱发的荨麻疹的患病率、临床表现、诊断方法和治疗的现有信息。
物理性荨麻疹在普通人群中的患病率高达5%,在慢性荨麻疹患者中为10%至50%。最近的研究表明,单独存在物理性荨麻疹或与慢性自发性荨麻疹合并存在时,与更差的预后和病程相关。物理性荨麻疹最常见的亚型是皮肤划痕症和迟发性压力性荨麻疹。通过特定的激发试验进行诊断,治疗包括避免措施、使用非镇静性抗组胺药的药物治疗以及难治性病例的替代药物。