Mendonca Goncalo V, Vaz João R, Teixeira Micael S, Grácio Telma, Pezarat-Correia Pedro
Laboratory of Motor Behavior, Faculty of Human Kinetics, University of Lisbon, Lisbon, Portugal.
Clin Physiol Funct Imaging. 2014 Jul;34(4):308-16. doi: 10.1111/cpf.12098. Epub 2013 Nov 18.
We explored whether interval walking with blood flow restriction (BFR) increases net metabolic cost of locomotion in healthy young men at their optimal walking speed. We also determined whether decreased walking economy resulting from BFR might be accompanied by an increase in ventilation relative to VO2 and VCO2 . Finally, we examined possible relationships between the changes in ratings of perceived exertion (RPE) and those obtained in minute ventilation (VE ) during walking with BFR. Eighteen healthy men (age: 22·5 ± 3·4 years) performed graded treadmill exercise to assess VO2max . In a randomized fashion, participants also performed five bouts of 3-min treadmill exercise with and without BFR at their optimal walking speed. Walking with BFR elicited an overall increase in net VO2 (10·4%) compared with that seen in the non-BFR condition (P<0·05). The participants also demonstrated greater VE and VE /VO2 values while walking with BFR (P<0·05). Conversely, VE /VCO2 was similar between conditions at each walking bout. We found no significant correlation between the changes in VE and RPE induced by walking with BFR (r = 0·38, P>0·05). Our results indicate that (i) BFR decreases net walking economy in healthy young men, even at their optimal walking speed; (ii) heightened ventilatory drive may explain a small proportion of BFR effects on walking economy; and (iii) the ventilatory responses to BFR walking may be largely independent of changes in perceived exertion and are likely matched to the flux of CO2 between muscles and respiratory centres.
我们探究了在健康年轻男性以最佳步行速度进行间歇性血流限制步行（BFR）时，是否会增加运动的净代谢成本。我们还确定了BFR导致的步行经济性下降是否可能伴随着相对于耗氧量（VO₂）和二氧化碳排出量（VCO₂）的通气增加。最后，我们研究了在进行BFR步行时，主观用力程度（RPE）的变化与每分通气量（VE）的变化之间可能存在的关系。18名健康男性（年龄：22.5±3.4岁）进行了递增式跑步机运动以评估最大摄氧量（VO₂max）。参与者还以随机方式在最佳步行速度下进行了5组3分钟的跑步机运动，包括有BFR和无BFR的情况。与无BFR条件相比，进行BFR步行时净VO₂总体增加（10.4%）（P<0.05）。参与者在进行BFR步行时也表现出更高的VE和VE/VO₂值（P<0.05）。相反，在每组步行时，不同条件下的VE/VCO₂相似。我们发现BFR步行引起的VE变化与RPE变化之间无显著相关性（r = 0.38，P>0.05）。我们的结果表明：（i）即使在最佳步行速度下，BFR也会降低健康年轻男性的净步行经济性；（ii）增强的通气驱动可能部分解释了BFR对步行经济性的影响；（iii）对BFR步行的通气反应可能在很大程度上独立于主观用力程度的变化，并且可能与肌肉和呼吸中枢之间的二氧化碳通量相匹配。
