乌黑白眉猴（Cercocebus atys）的血液学和血清化学值：与恒河猴的比较。
Hematology and serum chemistry values of sooty mangabeys (Cercocebus atys): comparison with rhesus monkeys.
作者信息
Sharma P, Chennareddi L, Greene-Hartsfield E Z, Villinger F, Cohen J K, Herndon J G
机构信息
Division of Pathology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA; Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
出版信息
J Med Primatol. 2014 Apr;43(2):78-88. doi: 10.1111/jmp.12091. Epub 2013 Nov 21.
BACKGROUND
The sooty mangabey is a vulnerable West African species that naturally harbors simian immunodeficiency virus (SIV) without pathological symptoms. We present normative hematology and serum chemistry values for this species.
METHODS
Hematology analytes from 136 females and 96 males and serum chemistry analytes from 57 females and 26 males were studied.
RESULTS
Values of several analytes fell outside published reference ranges in the rhesus monkey, a laboratory standard for Old World primates. Erythrocyte-related parameters were higher in mangabeys than in rhesus monkeys, while platelet counts were lower. Mangabeys also had higher gamma-glutamyltransferase levels and lower urea nitrogen levels. Males had higher erythrocyte-associated values than females. Albumin, globulin, albumin/globulin ratio, calcium, and creatinine changed with age in patterns similar to those reported for the rhesus monkey.
CONCLUSIONS
The unique blood profile of the mangabey should be taken into account in clinical and experimental studies of this species.
背景
乌白眉猴是一种濒危的西非物种，其自然携带猿猴免疫缺陷病毒（SIV）却无病理症状。我们给出了该物种的正常血液学和血清化学值。
方法
研究了136只雌性和96只雄性的血液学分析物以及57只雌性和26只雄性的血清化学分析物。
结果
几种分析物的值超出了恒河猴（旧世界灵长类动物的实验室标准）已发表的参考范围。乌白眉猴的红细胞相关参数高于恒河猴，而血小板计数较低。乌白眉猴的γ-谷氨酰转移酶水平也较高，尿素氮水平较低。雄性的红细胞相关值高于雌性。白蛋白、球蛋白、白蛋白/球蛋白比值、钙和肌酐随年龄变化的模式与恒河猴报道的相似。
结论
在该物种的临床和实验研究中应考虑乌白眉猴独特的血液特征。
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