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本文引用的文献

1
Retrospective study of the treatment of infantile hemangiomas using a combination of propranolol and pulsed dye laser.回顾性研究使用普萘洛尔联合脉冲染料激光治疗婴儿血管瘤。
Dermatol Surg. 2013 Jun;39(6):923-33. doi: 10.1111/dsu.12158. Epub 2013 Mar 4.
2
Initiation and use of propranolol for infantile hemangioma: report of a consensus conference.普萘洛尔治疗婴幼儿血管瘤:共识会议报告。
Pediatrics. 2013 Jan;131(1):128-40. doi: 10.1542/peds.2012-1691. Epub 2012 Dec 24.
3
Combined low-dose oral propranolol and oral prednisolone as first-line treatment in periocular infantile hemangiomas.联合低剂量口服普萘洛尔和口服泼尼松龙作为眶周婴儿血管瘤的一线治疗。
J Ocul Pharmacol Ther. 2011 Jun;27(3):309-11. doi: 10.1089/jop.2011.0013. Epub 2011 May 4.
4
Treatment guideline for hemangiomas and vascular malformations of the head and neck.头颈部血管瘤和脉管畸形治疗指南。
Head Neck. 2010 Aug;32(8):1088-98. doi: 10.1002/hed.21274.
5
Intralesional corticosteroid therapy in hemangiomas: clinical outcome in 160 cases.血管瘤的瘤内皮质类固醇治疗:160例临床结果
J Med Assoc Thai. 2008 Oct;91 Suppl 3:S90-6.
6
Propranolol for severe hemangiomas of infancy.普萘洛尔治疗婴儿重症血管瘤。
N Engl J Med. 2008 Jun 12;358(24):2649-51. doi: 10.1056/NEJMc0708819.
7
Evaluation and management of infantile hemangioma: an overview.婴儿血管瘤的评估与管理:概述
Ostomy Wound Manage. 2008 May;54(5):16-8, 20, 22-6, 28-9.
8
Involution of infantile haemangiomas after imiquimod 5% cream.5%咪喹莫特乳膏治疗后婴儿血管瘤的消退
Clin Exp Dermatol. 2008 Jul;33(4):446-9. doi: 10.1111/j.1365-2230.2007.02676.x. Epub 2008 May 15.
9
Laser treatment of pediatric vascular lesions: Port wine stains and hemangiomas.小儿血管病变的激光治疗:葡萄酒色斑和血管瘤。
J Am Acad Dermatol. 2008 Feb;58(2):261-85. doi: 10.1016/j.jaad.2007.10.492.
10
Topical imiquimod in the treatment of infantile hemangiomas: a retrospective study.外用咪喹莫特治疗婴幼儿血管瘤:一项回顾性研究。
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头颈部婴幼儿血管瘤治疗实用指南

A practical guide to treatment of infantile hemangiomas of the head and neck.

作者信息

Zheng Jia Wei, Zhang Ling, Zhou Qin, Mai Hua Ming, Wang Yan An, Fan Xin Dong, Qin Zhong Ping, Wang Xv Kai, Zhao Yi Fang

机构信息

Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine No. 639, Zhi Zao Ju Road, Shanghai 200011, China.

出版信息

Int J Clin Exp Med. 2013 Oct 25;6(10):851-60. eCollection 2013.

PMID:24260591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3832322/
Abstract

Infantile hemangiomas are the most common benign vascular tumors in infancy and childhood. As hemangioma could regress spontaneously, it generally does not require treatment unless proliferation interferes with normal function or gives rise to risk of serious disfigurement and complications unlikely to resolve without treatment. Various methods for treating infant hemangiomas have been documented, including wait and see policy, laser therapy, drug therapy, sclerotherapy, radiotherapy, surgery and so on, but none of these therapies can be used for all hemangiomas. To obtain the best treatment outcomes, the treatment protocol should be individualized and comprehensive as well as sequential. Based on published literature and clinical experiences, we established a treatment guideline in order to provide criteria for the management of head and neck hemangiomas. This protocol will be renewed and updated to include and reflect any cutting-edge medical knowledge, and provide the newest treatment modalities which will benefit our patients.

摘要

婴儿血管瘤是婴幼儿期最常见的良性血管肿瘤。由于血管瘤可自发消退,一般无需治疗,除非其增殖干扰正常功能或导致严重毁容风险以及若不治疗不太可能自行缓解的并发症。已有多种治疗婴儿血管瘤的方法被记录,包括观察等待策略、激光治疗、药物治疗、硬化治疗、放射治疗、手术等,但这些疗法均不能适用于所有血管瘤。为获得最佳治疗效果,治疗方案应个体化、全面且具有连贯性。基于已发表的文献和临床经验,我们制定了一项治疗指南,以便为头颈部血管瘤的管理提供标准。该方案将不断更新,纳入并反映任何前沿医学知识,提供能使我们的患者受益的最新治疗方式。