Biomedical Informatics Centre of ICMR, National Institute for Research in Reproductive Health, Mumbai 400012, Maharashtra, India.
Nucleic Acids Res. 2014 Jan;42(Database issue):D1154-8. doi: 10.1093/nar/gkt1157. Epub 2013 Nov 21.
Antimicrobial peptides (AMPs) are gaining importance as anti-infective agents. Here we describe the updated Collection of Antimicrobial Peptide (CAMP) database, available online at http://www.camp.bicnirrh.res.in/. The 3D structures of peptides are known to influence antimicrobial activity. Although there exists databases of AMPs, information on structures of AMPs is limited in these databases. CAMP is manually curated and currently holds 6756 sequences and 682 3D structures of AMPs. Sequence and structure analysis tools have been incorporated to enhance the usefulness of the database.
抗菌肽 (AMPs) 作为抗感染药物的重要性日益增加。在这里，我们描述了可在线获取的更新版抗菌肽集合 (CAMP) 数据库，网址为 http://www.camp.bicnirrh.res.in/。肽的 3D 结构已知会影响抗菌活性。虽然存在 AMPs 数据库，但这些数据库中关于 AMPs 结构的信息有限。CAMP 是人工整理的，目前包含 6756 个 AMPs 序列和 682 个 3D 结构。已合并序列和结构分析工具以增强数据库的实用性。
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