Yang Ju Yean, Kim Na Kyung, Lee Yun Jeong, Noh Jung Hyun, Kim Dae Jung, Ko Kyung Soo, Rhee Byoung Doo, Kim Dong-Jun
Department of Internal Medicine, Inje University College of Medicine, Busan, Republic of Korea.
Diabetes Res Clin Pract. 2013 Dec;102(3):218-24. doi: 10.1016/j.diabres.2013.10.016. Epub 2013 Nov 2.
We examined the prevalence and factors associated with diabetic retinopathy (DR) in a Korean adult population.
Fundus examination data from 10,345 people in the fourth Korea National Health and Nutrition Examination Survey from 2008 to 2009 were examined. For each participant, one 45° nonmydriatic digital retinal image, centered on the fovea, was taken per eye. DR was defined as the presence of one or more retinal microaneurysms or retinal blot hemorrhages with or without more severe lesions.
The weighted prevalence of DR was 0.9% (95% CI, 0.7-1.1) in a Korean adult population and 11.0% (95% CI, 8.9-13.6) in Korean adults with diabetes. In a logistic regression analysis, only HbA1c and diabetes duration were independently associated with DR; the other variables examined, including age, gender, exercise, current smoking, heavy alcohol drinking, presence of hypertension, total cholesterol, triglycerides, high-density lipoprotein cholesterol, anti-lipid medication, oral anti-diabetes treatment, and insulin treatment, were not associated with DR.
According to these national survey data, 1 in 10 people with diabetes has diabetic retinopathy. Glycemic control is the most important factor for preventing retinopathy in patients with diabetes.
我们调查了韩国成年人群中糖尿病视网膜病变（DR）的患病率及其相关因素。
对2008年至2009年韩国第四次全国健康与营养检查调查中10345人的眼底检查数据进行了分析。为每位参与者的每只眼睛拍摄一张以黄斑为中心的45°免散瞳数字视网膜图像。DR定义为存在一个或多个视网膜微动脉瘤或视网膜点状出血，伴有或不伴有更严重的病变。
韩国成年人群中DR的加权患病率为0.9%（95%CI，0.7 - 1.1），糖尿病成年患者中为11.0%（95%CI，8.9 - 13.6）。在逻辑回归分析中，只有糖化血红蛋白（HbA1c）和糖尿病病程与DR独立相关；所检查的其他变量，包括年龄、性别、运动、当前吸烟、大量饮酒、高血压、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、抗血脂药物、口服抗糖尿病治疗和胰岛素治疗，均与DR无关。
根据这些全国性调查数据，每10名糖尿病患者中有1人患有糖尿病视网膜病变。血糖控制是预防糖尿病患者视网膜病变的最重要因素。
