Muñoz A, García R A, Pérez-Aranda A
Antimicrob Agents Chemother. 1986 Jul;30(1):192-5. doi: 10.1128/AAC.30.1.192.
The antiviral action of different human interferons against encephalomyocarditis virus in HeLa cell cultures was analyzed. Cell treatment with levamisole (200 micrograms/ml), methisoprinol (1 mg/ml), or adenine or adenosine (33 or 100 micrograms/ml, respectively) potentiated the anti-encephalomyocarditis virus activity of human interferon by 8- to 32-fold. A higher level of potentiation (256-fold) was achieved either by combined treatments with levamisole plus methisoprinol or by treatment with one of these compounds plus adenine or adenosine.
分析了不同人类干扰素在HeLa细胞培养物中对脑心肌炎病毒的抗病毒作用。用左旋咪唑（200微克/毫升）、异丙肌苷（1毫克/毫升）或腺嘌呤或腺苷（分别为33或100微克/毫升）处理细胞，可使人类干扰素的抗脑心肌炎病毒活性增强8至32倍。通过左旋咪唑加异丙肌苷联合处理或用这些化合物之一加腺嘌呤或腺苷处理可实现更高水平的增强（256倍）。
