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本文引用的文献

1
The effect of dentifrice quantity and toothbrushing behaviour on oral delivery and retention of fluoride in vivo.牙膏用量和刷牙行为对体内氟化物经口腔输送和保留的影响。
Int Dent J. 2013 Dec;63 Suppl 2(Suppl 2):14-24. doi: 10.1111/idj.12075.
2
Cochrane reviews on the benefits/risks of fluoride toothpastes.关于含氟牙膏益处/风险的 Cochrane 综述。
J Dent Res. 2011 May;90(5):573-9. doi: 10.1177/0022034510393346. Epub 2011 Jan 19.
3
Preventive effect of high-fluoride dentifrice (5,000 ppm) in caries-active adolescents: a 2-year clinical trial.高氟牙膏(5000ppm)对龋齿活跃青少年的预防效果:一项为期 2 年的临床试验。
Caries Res. 2010;44(3):323-31. doi: 10.1159/000317490. Epub 2010 Jul 3.
4
The risk of enamel fluorosis and caries among Norwegian children: implications for Norway and the United States.挪威儿童的氟斑牙和龋齿风险:对挪威和美国的影响。
J Am Dent Assoc. 2010 Apr;141(4):401-14. doi: 10.14219/jada.archive.2010.0192.
5
The effect of brushing time and dentifrice quantity on fluoride delivery in vivo and enamel surface microhardness in situ.刷牙时间和牙膏用量对体内氟输送和表面微观硬度的影响。
Caries Res. 2010;44(2):90-100. doi: 10.1159/000284399. Epub 2010 Feb 16.
6
Fluoride toothpastes of different concentrations for preventing dental caries in children and adolescents.不同浓度的含氟牙膏预防儿童和青少年龋齿的效果
Cochrane Database Syst Rev. 2010 Jan 20(1):CD007868. doi: 10.1002/14651858.CD007868.pub2.
7
An update on fluorides and fluorosis.氟化物与氟中毒的最新情况
J Can Dent Assoc. 2003 May;69(5):286-91.
8
Caries rates for the mesial surface of the first permanent molar and the distal surface of the second primary molar from 6 to 12 years of age in Sweden.瑞典6至12岁儿童第一恒磨牙近中面和第二乳磨牙远中面的龋齿发病率。
Caries Res. 2000 Nov-Dec;34(6):454-61. doi: 10.1159/000016623.
9
Factors affecting dentifrice use and ingestion among a sample of U.S. preschoolers.影响美国学龄前儿童样本中牙膏使用和吞咽情况的因素。
Pediatr Dent. 2000 Sep-Oct;22(5):389-94.
10
Current concepts on the theories of the mechanism of action of fluoride.关于氟化物作用机制理论的当前概念。
Acta Odontol Scand. 1999 Dec;57(6):325-9. doi: 10.1080/000163599428562.

“豌豆大小的量”是多少?三个国家父母对牙膏剂量的研究。

How much is a 'pea-sized amount'? A study of dentifrice dosing by parents in three countries.

机构信息

GlaxoSmithKline Consumer Healthcare, Weybridge, UK.

出版信息

Int Dent J. 2013 Dec;63 Suppl 2(Suppl 2):25-30. doi: 10.1111/idj.12074.

DOI:10.1111/idj.12074
PMID:24283281
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9375012/
Abstract

To provide optimal fluoride effectiveness against caries while minimising risk of negative effects from excessive ingestion from toothbrushing, the fluoride dose delivered at each occasion is critical. This is particularly important for young children, so using a 'pea-sized amount' is generally recommended. However, there appears little guidance regarding what this means in practice, although it has been indicated to be 0.25 g. This study investigated, using conventional toothpastes and toothbrushes in Germany, the USA and the UK, how much toothpaste parents dispense for their 3- to 6 year-old children, and their interpretation of a 'pea-sized' amount of toothpaste. When asked to dispense the amount they would normally for their child, the majority of parents dosed substantially more than 0.25 g; in Germany, all parents over-dispensed. The amount dispensed varied widely: those parents at the 75th centile dispensed approximately twice the amount dispensed by those at the 25th centile, irrespective of country. When asked to dispense a pea-sized amount, the mean amount dosed decreased significantly in all countries. In the USA, electric toothbrush users dispensed about 0.1 g more than manual toothbrush users. While over-dispensing of fluoride toothpaste remains a cause for concern, it may be argued that the general recommendation to use a pea-sized amount of toothpaste generally works well in practice to balance the conflicting demands of risk and benefit from toothbrushing with fluoride toothpaste in young children.

摘要

为了在最小化因刷牙摄入过量而产生副作用风险的同时,提供针对龋齿的最佳氟化物效果,每次使用的氟化物剂量至关重要。这对于幼儿尤为重要,因此通常建议使用“豌豆大小”的量。然而,尽管已经表明这是 0.25 克,但实际上对于这意味着什么似乎几乎没有指导。本研究使用德国、美国和英国的常规牙膏和牙刷进行了研究,调查了父母为 3 至 6 岁儿童分配的牙膏量,以及他们对“豌豆大小”牙膏量的理解。当被要求分配他们通常会为孩子分配的量时,大多数父母分配的量远远超过 0.25 克;在德国,所有父母都分配过多。分配的量差异很大:那些处于第 75 百分位数的父母分配的量大约是处于第 25 百分位数的父母的两倍,而不论国家如何。当被要求分配豌豆大小的量时,所有国家的分配量都明显减少。在美国,电动牙刷使用者比手动牙刷使用者多分配约 0.1 克。虽然氟化物牙膏的过度分配仍然令人担忧,但可以说,一般建议使用豌豆大小的牙膏量,通常在实践中可以很好地平衡儿童使用含氟牙膏刷牙时的风险和收益之间的冲突需求。