GlaxoSmithKline Consumer Healthcare, Weybridge, UK.
Int Dent J. 2013 Dec;63 Suppl 2(Suppl 2):25-30. doi: 10.1111/idj.12074.
To provide optimal fluoride effectiveness against caries while minimising risk of negative effects from excessive ingestion from toothbrushing, the fluoride dose delivered at each occasion is critical. This is particularly important for young children, so using a 'pea-sized amount' is generally recommended. However, there appears little guidance regarding what this means in practice, although it has been indicated to be 0.25 g. This study investigated, using conventional toothpastes and toothbrushes in Germany, the USA and the UK, how much toothpaste parents dispense for their 3- to 6 year-old children, and their interpretation of a 'pea-sized' amount of toothpaste. When asked to dispense the amount they would normally for their child, the majority of parents dosed substantially more than 0.25 g; in Germany, all parents over-dispensed. The amount dispensed varied widely: those parents at the 75th centile dispensed approximately twice the amount dispensed by those at the 25th centile, irrespective of country. When asked to dispense a pea-sized amount, the mean amount dosed decreased significantly in all countries. In the USA, electric toothbrush users dispensed about 0.1 g more than manual toothbrush users. While over-dispensing of fluoride toothpaste remains a cause for concern, it may be argued that the general recommendation to use a pea-sized amount of toothpaste generally works well in practice to balance the conflicting demands of risk and benefit from toothbrushing with fluoride toothpaste in young children.
为了在最小化因刷牙摄入过量而产生副作用风险的同时,提供针对龋齿的最佳氟化物效果,每次使用的氟化物剂量至关重要。这对于幼儿尤为重要,因此通常建议使用“豌豆大小”的量。然而,尽管已经表明这是 0.25 克,但实际上对于这意味着什么似乎几乎没有指导。本研究使用德国、美国和英国的常规牙膏和牙刷进行了研究,调查了父母为 3 至 6 岁儿童分配的牙膏量,以及他们对“豌豆大小”牙膏量的理解。当被要求分配他们通常会为孩子分配的量时,大多数父母分配的量远远超过 0.25 克;在德国,所有父母都分配过多。分配的量差异很大:那些处于第 75 百分位数的父母分配的量大约是处于第 25 百分位数的父母的两倍,而不论国家如何。当被要求分配豌豆大小的量时,所有国家的分配量都明显减少。在美国,电动牙刷使用者比手动牙刷使用者多分配约 0.1 克。虽然氟化物牙膏的过度分配仍然令人担忧,但可以说,一般建议使用豌豆大小的牙膏量,通常在实践中可以很好地平衡儿童使用含氟牙膏刷牙时的风险和收益之间的冲突需求。