GlaxoSmithKline Consumer Healthcare, Weybridge, UK.
Int Dent J. 2013 Dec;63 Suppl 2(Suppl 2):57-63. doi: 10.1111/idj.12083.
A number of factors should be taken into account when designing toothpaste formulations for use by children at the different stages of their development. While adult toothpaste formulations may provide caries prevention benefits for children at risk of caries, these formulations may also contain higher levels of abrasive in order to address the staining needs of the adult population owing to smoking and the consumption of dietary chromogens such as coffee and tea, which are not normally found in the diet of children. While toothpastes formulated for adults are also likely to contain higher concentrations of surfactant and flavour, many children prefer toothpastes with mild flavours and modest foaming characteristics. An ideal children's toothpaste formulation should therefore aim to maximise fluoride availability, with appropriate abrasivity, while still delivering effective cleaning, as well as levels and types of flavour and surfactant to provide an acceptable brushing experience. Selection of toothpaste flavour types for children of different ages should ideally be based directly upon preference data from children. Flavours perceived as pleasant during brushing studies have been linked to increased brushing time, which, in turn, can increase the delivery and efficacy of fluoride from toothpastes. Therefore, manufacturers select tested, child-friendly flavours to maximise compliance, providing a more pleasurable brushing experience and oral health benefits.
在为处于不同发育阶段的儿童设计牙膏配方时,需要考虑许多因素。虽然成人牙膏配方可能为患龋齿风险较高的儿童提供防龋益处,但这些配方也可能含有更高水平的研磨剂,以解决因吸烟和食用膳食显色剂(如咖啡和茶)而导致的成年人群的染色问题,这些物质通常不存在于儿童的饮食中。尽管专为成人设计的牙膏也可能含有更高浓度的表面活性剂和香料,但许多儿童更喜欢味道温和、泡沫适中的牙膏。因此,理想的儿童牙膏配方应旨在最大限度地提高氟化物的可用性,同时具有适当的研磨性,并且仍能提供有效的清洁效果,以及提供可接受的刷牙体验的香料和表面活性剂的水平和类型。根据儿童的偏好数据,为不同年龄段的儿童选择牙膏口味类型是理想的。在刷牙研究中被认为是令人愉悦的口味与增加刷牙时间有关,而刷牙时间的增加又可以增加牙膏中氟化物的输送和功效。因此,制造商选择经过测试的、适合儿童的口味,以最大限度地提高顺应性,提供更愉快的刷牙体验和口腔健康益处。