Mohyuddin G R, Sultan F, Zhang K, Khaleeq G
Geisinger Medical Center - Danville, PA.
Sarcoidosis Vasc Diffuse Lung Dis. 2013 Nov 25;30(3):226-30.
A commonly prescribed drug for Rheumatoid Arthritis (R.A) and Inflammatory Bowel Disease (IBD) treatment, Sulfasalazine can occasionally cause lung toxicity such as interstitial pneumonitis and eosinophilic pneumonias. We report a case of a 46 year old female being treated with Sulfasalazine for Ulcerative Colitis, who developed shortness of breath and a radiographic pattern of hilar adenopathy. Biopsy showed granulomas that resembled Sarcoidosis. We review different presentations of Sulfasalazine induced lung disease and describe the first known case of Sulfasalazine lung toxicity mimicking Sarcoidosis.
柳氮磺胺吡啶是一种常用于治疗类风湿性关节炎（R.A）和炎症性肠病（IBD）的药物，偶尔会引起肺部毒性，如间质性肺炎和嗜酸性肺炎。我们报告了一例46岁女性，因溃疡性结肠炎接受柳氮磺胺吡啶治疗，出现呼吸急促和肺门淋巴结肿大的影像学表现。活检显示肉芽肿，类似于结节病。我们回顾了柳氮磺胺吡啶所致肺部疾病的不同表现，并描述了首例疑似结节病的柳氮磺胺吡啶肺毒性病例。
