Department of Biomedical Engineering, Ming Chuan University, No. 5 Deming Road, Guishan Township, Taoyuan County 333, Taiwan.
Evid Based Complement Alternat Med. 2013;2013:476565. doi: 10.1155/2013/476565. Epub 2013 Oct 31.
In a previous study, we found that the low-level laser (LLL) stimulation at the palm with a frequency of 10 Hz was able to induce significant brain activation in normal subjects with opened eyes. However, the electroencephalography (EEG) changes to LLL stimulation in subjects with closed eyes have not been studied. In the present study, the laser array stimulator was applied to deliver insensible laser stimulations to the palm of the tested subjects with closed eyes (the laser group). The EEG activities before, during, and after the laser stimulation were collected. The EEG amplitude powers of each EEG frequency band at 19 locations were calculated. These power data were then analyzed by SPSS software using repeated-measure ANOVAs and appropriate posthoc tests. We found a pronounced decrease in the EEG power in alpha-bandwidth during laser simulation and then less decrease in the EEG power in delta-bandwidth in normal subjects with laser stimulation. The EEG power in beta-bandwidth in the right occipital area also decreased significantly in the laser group. We suggest that LLL stimulation might be conducive to falling into sleep in patients with sleep problems.
在之前的研究中，我们发现，在睁眼的正常受试者中，用频率为 10Hz 的低水平激光（LLL）刺激手掌可以引起显著的大脑激活。然而，对于闭眼的受试者，LLL 刺激的脑电图（EEG）变化尚未被研究。在本研究中，激光阵列刺激器用于向闭眼测试对象的手掌提供不可察觉的激光刺激（激光组）。在激光刺激之前、期间和之后采集 EEG 活动。计算了 19 个位置的每个 EEG 频带的 EEG 幅度功率。然后使用 SPSS 软件对这些功率数据进行重复测量方差分析和适当的事后检验分析。我们发现，在正常受试者中，激光刺激期间 alpha 频带的 EEG 功率明显下降，然后 delta 频带的 EEG 功率下降较少。右侧枕区的 EEG 功率在 beta 频带也显著降低。我们认为，LLL 刺激可能有助于有睡眠问题的患者入睡。
