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阿瓦士地区头颈部鳞状细胞癌病因因素的发病率

Incidence of etiologic factors in squamous cell carcinoma of head and neck in ahvaz.

作者信息

Nikakhlagh Soheila, Saki Nader, Shoar Mahmood Hekmat, Sartipipor Amin, Saki Sara

机构信息

Associated Prof. of Otorhinolaryngology of imam Khomeini hospital.

出版信息

Iran J Otorhinolaryngol. 2012 Spring;24(67):85-90.

Abstract

INTRODUCTION

Squamous cell carcinoma (SCC) is the most common head and neck malignancy. Smoking, alcohol consumption, viral infections, exposure, oral hygiene, and dietary, genetic, and occupational factors are the most important etiologic factors. The aim of this study was determining the incidence of etiologic factors in head and neck SCC.

MATERIALS AND METHODS

This is a cross-sectional survey study for the determination of the etiologic factors of head and neck squamous cell carcinoma over a five-year period in the Otolaryngology Department of the Imam Khomeini & Golestan hospitals in Ahwaz.

RESULTS

176 patients, comprising 151(85.8%) men and 25(14.2%) women, were studied. Overall mean age was 67.2 years. 148 (84.1%) patients were smokers. prolong exposure to chemical fertilizer in 101 (57.4%) patients, Sun exposure in 21 (11.9%) patients, Low socioeconomic status in 124 (70.5%) patients, poor oral hygiene in 128 (72.7%) patients, high intake of hot tea drinking in 84 (47.7%) patients and malignancies in family in 12 (6.8%) patients were the most frequent risk factors. 17 (9.6%) patients have had opioid addiction and HPV was positive in 7 (3.9%) patients by PCR.

CONCLUSION

According to this study, tobacco smoking was the most important etiologic factor and had a strong effect on risk of head and neck squamous cell carcinoma. Other factors are also important and need more research study.

摘要

引言

鳞状细胞癌(SCC)是头颈部最常见的恶性肿瘤。吸烟、饮酒、病毒感染、暴露、口腔卫生以及饮食、遗传和职业因素是最重要的病因。本研究的目的是确定头颈部鳞状细胞癌病因的发生率。

材料与方法

这是一项横断面调查研究,旨在确定阿瓦士伊玛目霍梅尼医院和戈勒斯坦医院耳鼻喉科在五年期间头颈部鳞状细胞癌的病因。

结果

共研究了176例患者,其中男性151例(85.8%),女性25例(14.2%)。总体平均年龄为67.2岁。148例(84.1%)患者吸烟。101例(57.4%)患者长期接触化肥,21例(11.9%)患者长期暴露于阳光下,124例(70.5%)患者社会经济地位低,128例(72.7%)患者口腔卫生差,84例(47.7%)患者大量饮用热茶,12例(6.8%)患者有家族恶性肿瘤史,这些是最常见的危险因素。17例(9.6%)患者有阿片类药物成瘾史,7例(3.9%)患者经聚合酶链反应检测人乳头瘤病毒呈阳性。

结论

根据本研究,吸烟是最重要的病因,对头颈部鳞状细胞癌的风险有很大影响。其他因素也很重要,需要更多的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6518/3846216/d82c0532f85f/IJO-24-85-g001.jpg

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