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溃疡性结肠炎患者的c-ANCA相关性血管炎:病例报告

c-ANCA associated vasculitis in patients with ulcerative colitis: case report.

作者信息

dos Santos Cristiane Engel, Dal Pizzol Vanessa Irusta, Aragão Salun Coelho, Rachid Filho Acir, Marques Fabrício Machado

出版信息

Rev Bras Reumatol. 2013 Sep-Oct;53(5):441-3.

PMID:24316902
Abstract

The pulmonary manifestations of ulcerative colitis (UC) are rare and include inflammation of small and large airways, parenchymal disease and serositis among others. A substantial proportion of patients with inflammatory bowel disease, particularly those with ulcerative colitis presents positive ANCA, most p-ANCA pattern. We present a case of patient with ulcerative colitis, with positive c-ANCA, which progressed to hemoptysis associated with radiological findings consistent with pulmonary vasculitis.

摘要

溃疡性结肠炎(UC)的肺部表现较为罕见,包括小气道和大气道炎症、实质性疾病以及浆膜炎等。相当一部分炎症性肠病患者,尤其是溃疡性结肠炎患者ANCA呈阳性,多数为p-ANCA型。我们报告一例溃疡性结肠炎患者,其c-ANCA呈阳性,病情进展为咯血,影像学表现符合肺血管炎。

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引用本文的文献

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Exploring ANCA Pathogenicity in Ulcerative Colitis: A Case Report Highlighting the Risk of Progression to ANCA-Associated Vasculitis.探索溃疡性结肠炎中抗中性粒细胞胞浆抗体(ANCA)的致病性:一例报告凸显进展为ANCA相关血管炎的风险
Eur J Case Rep Intern Med. 2025 May 5;12(5):005061. doi: 10.12890/2025_005061. eCollection 2025.
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ANCA-associated vasculitis in a patient with enteropathic spondylarthritis: a case report and literature review.肠病性关节炎相关的抗中性粒细胞胞质抗体相关性血管炎:病例报告及文献复习。
Clin Rheumatol. 2021 Aug;40(8):3351-3355. doi: 10.1007/s10067-021-05612-y. Epub 2021 Jan 30.
3
Lung involvement in childhood onset granulomatosis with polyangiitis.
儿童期起病的显微镜下多血管炎的肺部受累情况。
Pediatr Rheumatol Online J. 2017 Apr 14;15(1):28. doi: 10.1186/s12969-017-0150-8.