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溃疡性结肠炎患者的c-ANCA相关性血管炎:病例报告

c-ANCA associated vasculitis in patients with ulcerative colitis: case report.

作者信息

dos Santos Cristiane Engel, Dal Pizzol Vanessa Irusta, Aragão Salun Coelho, Rachid Filho Acir, Marques Fabrício Machado

出版信息

Rev Bras Reumatol. 2013 Sep-Oct;53(5):441-3.

Abstract

The pulmonary manifestations of ulcerative colitis (UC) are rare and include inflammation of small and large airways, parenchymal disease and serositis among others. A substantial proportion of patients with inflammatory bowel disease, particularly those with ulcerative colitis presents positive ANCA, most p-ANCA pattern. We present a case of patient with ulcerative colitis, with positive c-ANCA, which progressed to hemoptysis associated with radiological findings consistent with pulmonary vasculitis.

摘要

溃疡性结肠炎(UC)的肺部表现较为罕见,包括小气道和大气道炎症、实质性疾病以及浆膜炎等。相当一部分炎症性肠病患者,尤其是溃疡性结肠炎患者ANCA呈阳性,多数为p-ANCA型。我们报告一例溃疡性结肠炎患者,其c-ANCA呈阳性,病情进展为咯血,影像学表现符合肺血管炎。

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