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博来霉素所致肺部病变:计算机断层扫描观察结果

Bleomycin lung: computed tomographic observations.

作者信息

Rimmer M J, Dixon A K, Flower C D, Sikora K

出版信息

Br J Radiol. 1985 Nov;58(695):1041-5. doi: 10.1259/0007-1285-58-695-1041.

Abstract

Changes characteristic of bleomycin lung were seen in 15 out of 18 patients whose lungs were examined by computed tomography following standard chemotherapy for testicular cancers. These changes affected mainly the posterior aspects of the lungs and were predominantly subpleural in nature. The total dose of bleomycin given did not appear to correlate with the grade of bleomycin damage. Amongst six patients with adequate follow-up studies there has been improvement in the CT appearance of three.

摘要

在接受睾丸癌标准化疗后通过计算机断层扫描检查肺部的18例患者中,有15例出现了博来霉素所致肺部改变的特征。这些改变主要影响肺的后部,本质上多位于胸膜下。给予的博来霉素总剂量似乎与博来霉素损伤的程度无关。在6例有充分随访研究的患者中,有3例的CT表现有所改善。

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