具有内在过氧化物酶样催化活性的水稳定金属有机框架作为比色生物传感平台
Water-stable metal-organic frameworks with intrinsic peroxidase-like catalytic activity as a colorimetric biosensing platform.
作者信息
Zhang Jian-Wei, Zhang Hao-Tian, Du Zi-Yi, Wang Xueqing, Yu Shu-Hong, Jiang Hai-Long
机构信息
Hefei National Laboratory for Physical Sciences at the Microscale, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, P.R. China.
出版信息
Chem Commun (Camb). 2014 Feb 4;50(9):1092-4. doi: 10.1039/c3cc48398c.
Two iron(III)-based metal-organic frameworks (MOFs) are found to behave as efficient peroxidase mimics and catalyze the oxidation of different peroxidase substrates by H2O2 accompanied with significant color change in the solution. With these findings, a simple and sensitive colorimetric assay to detect H2O2 and ascorbic acid has been established.
发现两种基于铁（III）的金属有机框架（MOF）表现为高效的过氧化物酶模拟物，并催化过氧化氢对不同过氧化物酶底物的氧化，同时溶液中伴有明显的颜色变化。基于这些发现，建立了一种简单灵敏的比色法来检测过氧化氢和抗坏血酸。
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