Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA,
Transl Stroke Res. 2011 Mar;2(1):17-25. doi: 10.1007/s12975-010-0037-1. Epub 2010 Aug 10.
Although intracerebral hemorrhage (ICH) has no proven treatment, well-designed studies using animal models of ICH may lead to the development of novel therapies. We briefly review current animal models of ICH. Furthermore, we discuss how these models may be utilized and targeted to facilitate translation of preclinical findings to the clinical arena.
虽然脑出血(ICH)尚无有效的治疗方法,但使用 ICH 动物模型进行精心设计的研究可能会为新疗法的开发提供依据。我们简要回顾了当前的 ICH 动物模型。此外,我们还讨论了如何利用和针对这些模型,以促进将临床前研究结果转化为临床应用。