Chakraborty Sanghamitra, Chakraborty Indranil
Department of Biochemistry, Medical College, 88th College Street, Kolkata 700073, India.
Biochem Res Int. 2013;2013:590791. doi: 10.1155/2013/590791. Epub 2013 Nov 14.
Reference interval of all haematological and biological analytes should be measured for every population because of the huge diversity in genetic make-up, dietary habits. The coverage interval of antioxidant vitamins (vitamin C and α -tocopherol) in the plasma and serum of reference Bengali population was determined and compared with the reference intervals of antioxidant vitamins in the established literature. Adult healthy volunteers from 18 to 68 years of age underwent extensive clinical and investigational procedure and were included in the study. Vitamin C and α -tocopherol were estimated using simple Spectrophotometric method. Of the 71 healthy Bengali volunteers participated, 31 were males and 40 were females. The mean concentration of plasma vitamin C was found to be 0.65 mg/dL. The mean α -tocopherol was found 6.35 mg/L (14.74 μ mol/L) in the study population higher than the normal threshold value for α -tocopherol but lower than other populations. The study data enabled us to determine the gender nonspecific coverage interval of antioxidant vitamins, and the intervals were lower than the established reference interval in other populations.
由于基因构成、饮食习惯存在巨大差异,每个群体都应测定所有血液学和生物学分析物的参考区间。本研究测定了孟加拉参考人群血浆和血清中抗氧化维生素(维生素C和α-生育酚)的覆盖区间,并与现有文献中抗氧化维生素的参考区间进行比较。18至68岁的成年健康志愿者接受了广泛的临床和检查程序,并纳入研究。采用简单的分光光度法测定维生素C和α-生育酚。在参与研究的71名健康孟加拉志愿者中,31名男性,40名女性。研究人群中血浆维生素C的平均浓度为0.65mg/dL。研究人群中α-生育酚的平均浓度为6.