Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.
Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.
Trends Microbiol. 2014 Jan;22(1):42-7. doi: 10.1016/j.tim.2013.11.003. Epub 2013 Dec 9.
The report of methicillin-resistant Staphylococcus aureus (MRSA) encoding a divergent mecA gene in 2011 was highly significant. This homologue, designated mecC, poses diagnostic problems with the potential to be misdiagnosed as methicillin-sensitive S. aureus, with important potential consequences for individual patients and for the surveillance of MRSA. mecC MRSA have now been reported from 13 European countries and have been isolated from 14 different host species, with evidence of a recent increase in Denmark. The emergence of mecC MRSA is a topic of interest to human and veterinary microbiology, and we consider it timely to review here its discovery and subsequent investigation.
2011 年报告的耐甲氧西林金黄色葡萄球菌（MRSA）编码一种不同的 mecA 基因具有重要意义。这种同源物被命名为 mecC，它与潜在的被误诊为甲氧西林敏感金黄色葡萄球菌有关，这对个体患者和 MRSA 的监测具有重要的潜在影响。mecC 耐甲氧西林金黄色葡萄球菌现已在 13 个欧洲国家报告，并从 14 种不同的宿主物种中分离出来，丹麦有证据表明最近有所增加。mecC 耐甲氧西林金黄色葡萄球菌的出现是人类和兽医微生物学关注的一个话题，我们认为及时对其发现和随后的研究进行回顾是很有意义的。
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