Dieterle R, Pillekamp H
Fachsanitätszentrum Leipzig , Kornblumenweg 4, 04158, Leipzig, Deutschland,
Hautarzt. 2014 Feb;65(2):125-9. doi: 10.1007/s00105-013-2725-8.
The German S1 guidelines from 2009 contain a variety of recommendations for the treatment of cutaneous leishmaniasis.
We report the results of our diagnostic procedures and treatment of 32 international patients in autumn 2010 in northern Afghanistan.
Giemsa stain confirmed the clinical diagnosis within 24 hours. Eleven simple lesions and one larger ulcer responded well to cryotherapy and intralesional sodium stibogluconate. More complex lesions in 19 patients responded well to oral miltefosine. One patient refused outpatient therapy.
Cryotherapy and intralesional antimony compounds showed good results in early lesions of cutaneous leishmaniasis in northern Afghanistan. Outpatient treatment of complex lesions with miltefosine was successful in all cases.
2009年德国S1指南包含了多种皮肤利什曼病的治疗建议。
我们报告了2010年秋季在阿富汗北部对32名国际患者进行诊断和治疗的结果。
吉姆萨染色在24小时内确诊了临床诊断。11个简单皮损和1个较大溃疡对冷冻疗法和病灶内注射葡糖酸锑钠反应良好。19例患者的更复杂皮损对口服米替福新反应良好。1例患者拒绝门诊治疗。
冷冻疗法和病灶内注射锑化合物在阿富汗北部皮肤利什曼病的早期皮损中显示出良好效果。用米替福新门诊治疗复杂皮损在所有病例中均获成功。
