Fernandes G S, Corrêa T S, Carvalho E P B, Katz A, Hoff P M
Oncology Center, Hospital Sírio-Libanês, Unidade Brasília, Brasília, Brazil.
Instituto do Câncer do Estado de São Paulo, São Paulo, Brazil.
Case Rep Oncol. 2013 Nov 6;6(3):555-60. doi: 10.1159/000356564. eCollection 2013.
Invasive lobular carcinoma (ILC) is the second most common histological type of invasive breast carcinoma, preceded only by infiltrating ductal carcinoma, which has clinical, biological and molecular distinctions. These distinctions imply a different metastatic behavior between the histology of these 2 types of breast cancer.
We report the case of a 51-year-old woman with breast cancer with ILC histology, diagnosed at an early stage. In the course of her disease, recurrences in the gastric mucosa and endobronchial area occurred. The treatment she received is described herein.
This is a case of ILC with unusual metastases. The absence of E-cadherin is related to the carcinogenesis of ILC and probably to these patterns of metastasis as well.
浸润性小叶癌（ILC）是浸润性乳腺癌的第二常见组织学类型，仅次于浸润性导管癌，两者在临床、生物学和分子方面存在差异。这些差异意味着这两种类型乳腺癌的组织学之间存在不同的转移行为。
我们报告一例51岁患有浸润性小叶癌组织学类型乳腺癌的女性患者，该患者在早期被诊断。在其病程中，胃黏膜和支气管内区域出现复发。本文描述了她接受的治疗。
这是一例具有不寻常转移的浸润性小叶癌病例。E-钙黏蛋白的缺失与浸润性小叶癌的致癌作用有关，可能也与这些转移模式有关。
