血小板受体；血小板生理学的一种工具。
Platelet receptors; an instrumental of platelet physiology.
作者信息
Saboor Muhammad, Ayub Qamar, Ilyas Samina
机构信息
Muhammad Saboor, Baqai Institute of Hematology, Baqai Medical University, Karachi, Pakistan.
Qamar Ayub, Baqai Institute of Medical Technology, Baqai Medical University, Karachi, Pakistan.
出版信息
Pak J Med Sci. 2013 May;29(3):891-6. doi: 10.12669/pjms.293.3497.
Abstract
Platelets play an important role in hemostasis, inflammation, host defense, tumor growth and metastasis. Platelets receptors are instrumental in platelet-platelet aggregation and interaction of platelets with leukocytes, endothelial cells and coagulation factors. These receptors are also the targets for antiplatelet drugs. This review focuses on the role of platelet receptors in human physiology. Data were extracted from peer-reviewed journals using MEDLINE and EMBASE databases, and the following terms (platelets, platelet receptors, CD markers, integrins, tetraspanins, transmembrane receptors, prostaglandin receptors, immunoglobulin superfamily receptors) were used.
摘要
血小板在止血、炎症、宿主防御、肿瘤生长和转移中发挥着重要作用。血小板受体在血小板与血小板的聚集以及血小板与白细胞、内皮细胞和凝血因子的相互作用中起重要作用。这些受体也是抗血小板药物的作用靶点。本综述重点关注血小板受体在人体生理学中的作用。使用MEDLINE和EMBASE数据库从同行评审期刊中提取数据，并使用了以下术语（血小板、血小板受体、CD标志物、整合素、四跨膜蛋白、跨膜受体、前列腺素受体、免疫球蛋白超家族受体）。
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