Moshe Fridman is with AMF Consulting, Los Angeles, CA. Lisa M. Korst is with the Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, and Childbirth Research Associates, LLC, Los Angeles. Jessica Chow is with the Departments of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles (UCLA). Kimberly D. Gregory is with the Departments of Obstetrics and Gynecology, Cedars Sinai Medical Center and David Geffen School of Medicine, UCLA. Elizabeth Lawton is with the Maternal, Child and Adolescent Health Division, California Department of Public Health, Sacramento, under contract with the University of California San Francisco. Connie Mitchell is with the California Department of Public Health, Maternal, Child and Adolescent Health Division, Sacramento.
Am J Public Health. 2014 Feb;104 Suppl 1(Suppl 1):S49-57. doi: 10.2105/AJPH.2013.301583. Epub 2013 Dec 19.
We examined trends in maternal comorbidities in California.
We conducted a retrospective cohort study of 1,551,017 California births using state-linked vital statistics and hospital discharge cohort data for 1999, 2002, and 2005. We used International Classification of Diseases, Ninth Revision, Clinical Modification codes to identify the following conditions, some of which were preexisting: maternal hypertension, diabetes, asthma, thyroid disorders, obesity, mental health conditions, substance abuse, and tobacco use. We estimated prevalence rates with hierarchical logistic regression models, adjusting for demographic shifts, and also examined racial/ethnic disparities.
The prevalence of these comorbidities increased over time for hospital admissions associated with childbirth, suggesting that pregnant women are getting sicker. Racial/ethnic disparities were also significant. In 2005, maternal hypertension affected more than 10% of all births to non-Hispanic Black mothers; maternal diabetes affected nearly 10% of births to Asian/Pacific Islander mothers (10% and 43% increases, respectively, since 1999). Chronic hypertension, diabetes, obesity, mental health conditions, and tobacco use among Native American women showed the largest increases.
The prevalence of maternal comorbidities before and during pregnancy has risen substantially in California and demonstrates racial/ethnic disparity independent of demographic shifts.
我们考察了加利福尼亚州产妇合并症的趋势。
我们对 1999 年、2002 年和 2005 年的加利福尼亚州 1551017 例出生进行了一项基于人群的回顾性队列研究,使用州际生命统计和住院患者队列数据。我们使用国际疾病分类,第九版,临床修正版的代码来确定以下情况,其中一些是先前存在的:产妇高血压、糖尿病、哮喘、甲状腺疾病、肥胖、心理健康状况、药物滥用和吸烟。我们使用分层逻辑回归模型估计了患病率,调整了人口统计学变化,还检查了种族/民族差异。
与分娩相关的住院患者的这些合并症的患病率随着时间的推移而增加,这表明孕妇的病情正在恶化。种族/民族差异也很显著。2005 年,非西班牙裔黑人产妇的所有分娩中,高血压的发病率超过 10%;亚裔/太平洋岛民产妇的糖尿病发病率接近 10%(自 1999 年以来分别增加了 10%和 43%)。慢性高血压、糖尿病、肥胖、心理健康状况和吸烟在美洲原住民妇女中增幅最大。
加利福尼亚州妊娠前和妊娠期间产妇合并症的患病率大幅上升,且表明种族/民族差异独立于人口统计学变化。