From the Oregon Health & Science University, Portland, Oregon (GLK, W-HJ, TAH, CED, RS, JJP); Warner Pacific College, Portland, Oregon (GHR); University of Florida, Gainesville (EMA); University of Illinois, Chicago (GTF); Baylor College of Medicine, Houston, Texas (MAN); and Oregon State University, Corvallis (BJC).
Am J Phys Med Rehabil. 2014 Jan;93(1):56-74. doi: 10.1097/PHM.0b013e3182a517e6.
The aim of this study was to determine the conceptual framework, item pool, and psychometric properties of a new function-neutral measure of health-related quality-of-life (HRQOL).
This is an expert panel review of existing measures of HRQOL and development of a conceptual model, core constructs, and item pool and a validation by experts in specific disabilities and in cultural competence. Items were cognitively tested, pilot tested for functional bias, field tested with a national sample of adults with various limitations, and reliability tested via repeat administration. Final item selection was based on analyses of factor structure, demographic bias, variance in likelihood of endorsement, and item-total correlation. Psychometric properties were demonstrated through differential item functioning analyses, factor analyses, correlations, and item response theory analyses.
The results supported a four-domain conceptual model of HRQOL (physical health, mental health, social health, and life satisfaction and beliefs) for a 42-item HRQOL measure with an ancillary 15-item environment scale. The measure has strong internal consistency (α = 0.88-0.97), known-groups validity, and test-retest reliability (r = 0.83-0.91). Tests of convergent and divergent validity confirmed the ability of the Function-Neutral Health-Related Quality of Life to measure health while being relatively free of content assessing function.
A conceptually grounded four-domain, function-neutral measure of HRQOL that is appropriate for use with persons with and without various functional limitations was developed.
本研究旨在确定健康相关生活质量（HRQOL）新的功能中立测量方法的概念框架、项目池和心理测量特性。
这是对现有 HRQOL 测量方法的专家小组审查，并开发了概念模型、核心结构以及项目池，并由特定残疾和文化能力方面的专家进行了验证。对项目进行了认知测试、针对功能偏差进行了试点测试、对具有各种限制的全国性成年人样本进行了现场测试，并通过重复管理进行了可靠性测试。最终项目选择基于对因素结构、人口统计学偏差、可能性差异的分析、以及项目与总分的相关性。通过差异项目功能分析、因素分析、相关性和项目反应理论分析来证明心理测量特性。
结果支持了 HRQOL 的四个领域概念模型（身体健康、心理健康、社会健康以及生活满意度和信念），用于 42 项 HRQOL 测量方法和一个辅助的 15 项环境量表。该测量方法具有很强的内部一致性（α=0.88-0.97）、已知组有效性和重测信度（r=0.83-0.91）。收敛和发散有效性测试证实了功能中立的健康相关生活质量测量方法在评估功能的同时测量健康的能力。
开发了一种具有概念基础的、四个领域的、功能中立的 HRQOL 测量方法，适用于有和没有各种功能限制的人。
